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23 results for "other-kinase-compounds&view=expanded" in Products

Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7

GMP Version Available: TB1614-GMP
GMP
Chemical Name:
4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Purity:
≥99%
dopaminergic neurons derived from hiPSCs using SB 431542
(2)

Potent AMPK inhibitor; also BMP type I receptor inhibitor

Alternate Names:
Compound C,BML-275
Chemical Name:
6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine dihydrochloride
Purity:
≥98%
Potent AMPK inhibitor; also BMP type I receptor inhibitor

Selective inhibitor of TGF-βRI, ALK4 and ALK7

Chemical Name:
3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
Purity:
≥98%
Adult Stem Cell-derived Liver Organoids
(6)

Potent pan-salt inducible kinases (SIK1, SIK2 and SIK3) inhibitor. Also inhibits Lat-B-induced EP differentiation via nuclear YAP1 accumulation.

Alternate Names:
SIK inhibitor 1
Chemical Name:
1-(2,4-Dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-(6-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)urea
Purity:
≥98%
Potent pan-salt inducible kinases (SIK1, SIK2 and SIK3) inhibitor. Also inhibits Lat-B-induced EP differentiation via nuclear YAP1 accumulation.

Potent LMTK3 inhibitor

Chemical Name:
6-(Pyridin-4-yl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazine
Purity:
≥98%
Potent LMTK3 inhibitor

Potent LMTK3 inhibitor

Chemical Name:
6-(Pyridin-4-yl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazine
Purity:
≥98%
Potent LMTK3 inhibitor

Stimulates RhoA activation; antiproliferative agent that slows cell cycle progression

Chemical Name:
(2S,3R,4S,4aR)-3,4,4a,5-Tetrahydro-2,3,4,7-tetrahydroxy-(1,3)dioxolo(4,5-j)phenanthridin-6(2H)-one
Purity:
≥98%
Stimulates RhoA activation; antiproliferative agent that slows cell cycle progression

High affinity PKC activator; also APP modulator

Chemical Name:
(2E,4E)-N-[(2S,5S)-1,2,3,4,5,6-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-2,4-pentadienamide
Purity:
≥98%
High affinity PKC activator; also APP modulator

Potent and selective PIKfyve inhibitor

Chemical Name:
4-(6-(2-(3-Methylbenzylidene)hydrazinyl)-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholine dimethanesulfonate
Purity:
≥98%
Potent and selective PIKfyve inhibitor

MAP4K4 (HGK) inhibitor; also inhibits MINK and TNIK

Chemical Name:
5-(4-Chlorophenyl)-[3,3'-bipyridine]-6,6'-diamine dihydrochloride
Purity:
≥98%
MAP4K4 (HGK) inhibitor; also inhibits MINK and TNIK
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