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Other ER Stress/UPR Activators: Small Molecules and Peptides

Endoplasmic reticulum (ER) stress happens when the protein synthesis requirements of the cell exceed the protein folding capacity of the ER. Improperly folded proteins accumulate in the ER. This triggers the unfolded protein response (UPR) to restore ER homeostasis.

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4 results for "Other ER Stress/UPR Activators Small Molecules and Peptides" in Products

4 results for "Other ER Stress/UPR Activators Small Molecules and Peptides" in Products

Other ER Stress/UPR Activators: Small Molecules and Peptides

Endoplasmic reticulum (ER) stress happens when the protein synthesis requirements of the cell exceed the protein folding capacity of the ER. Improperly folded proteins accumulate in the ER. This triggers the unfolded protein response (UPR) to restore ER homeostasis.

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Integrated stress response (ISR) inhibitor

Chemical Name: N,N'-trans-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)acetamide]
Purity: ≥98% (HPLC)
Integrated stress response (ISR) inhibitor

Selective inhibitor of ATF6α; sensitizes cells to ER stress

Chemical Name: N-[1-[[2,4-bis(Trifluoromethyl)phenyl]methyl]-1H-pyrazol-4-yl]-5-(2-furanyl)-3-isoxazolecarboxamide
Purity: ≥98% (HPLC)
Selective inhibitor of ATF6α; sensitizes cells to ER stress

ER proteostasis regulator

Chemical Name: N-(2-Hydroxy-5-methylphenyl)benzenepropanamide
Purity: ≥98% (HPLC)
ER proteostasis regulator

SERCA2 allosteric activator

Chemical Name: 4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide
Purity: ≥98% (HPLC)
SERCA2 allosteric activator
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