Skip to main content

7 results for "Nrf2 Small Molecules and Peptides" in Products

Nrf2: Small Molecules and Peptides

NF-E2 related factor 2 (Nrf2) is a member of the cap 'n collar family of basic leucine zipper transcription factors. By binding antioxidant response elements (AREs), Nrf2 activates the transcription of genes encoding antioxidant and phase II drug-metabolizing enzymes needed to protect cells against oxidative damage. Transcriptional targets regulated by Nrf2 include genes encoding glutathione S-transferases, superoxide dismutase-1, and heme oxygenase-1.

Covalent allosteric NRF2 inhibitor

Chemical Name: 1-[(3R)-3-[3-(4-Amino-1,3,5-triazin-2-yl)-5-chlorophenyl]-4-morpholinyl]-2-propen-1-one
Purity: ≥98% (HPLC)
Covalent allosteric NRF2 inhibitor

Nrf2 inhibitor; phenotypically lethal

Chemical Name: N-[4-[2,3-Dihydro-1-(2-methylbenzoyl)-1H-indol-5-yl]-5-methyl-2-thiazolyl]-1,3-benzodioxole-5-acetamide
Purity: ≥98% (HPLC)
Nrf2 inhibitor; phenotypically lethal

Nrf2 activator; cell permeable

Chemical Name: 2-Methylenebutanedioic acid 4-octyl ester
Purity: ≥98% (HPLC)
Nrf2 activator; cell permeable

Nrf2 activator; inhibits Nrf2/Keap1 interaction

Chemical Name: (3S)-1-[4-[[(2,3,5,6-Tetramethylphenyl)sulfonyl]amino]-1-naphthalenyl]-3-pyrrolidinecarboxylic acid
Purity: ≥98% (HPLC)
Nrf2 activator; inhibits Nrf2/Keap1 interaction

PGK1 inhibitor; activates Nrf2

Chemical Name: (3R,4S)-rel-4-[(4-Chlorophenyl)sulfonyl]tetrahydro-N-(2-methylpropyl)-3-thiophenamine-1,1-dioxide
Purity: ≥98% (HPLC)
PGK1 inhibitor; activates Nrf2

Nrf2 signaling activator

Chemical Name: 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole
Purity: ≥98% (HPLC)
Nrf2 signaling activator

Nrf2 activator

Chemical Name: N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N'-(2-pyridinylmethyl)urea
Purity: ≥98% (HPLC)
Nrf2 activator
Results Per Page
5 10 25 50
/ 1