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MMP-8 Products

The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).

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296 results for "MMP-8" in Products

296 results for "MMP-8" in Products

MMP-8 Products

The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).

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Applications: ELISA
Human Total MMP-8 Standard Curve
(4)

Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies

Profiling Angiogenesis-Related Proteins in Human Cancer Tissues.
(3)
Source: NS0
Accession #: AAZ38714
Applications: EnzAct
R&D Systems Recombinant Proteins and Enzymes

Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.

Applications: NULL
Human MMP Luminex Assay Standard Curves
(2)

Contains 4 membranes - each spotted in duplicate with 35 different protease antibodies

Assay Range: 62.5 - 4,000 pg/mL
Applications: ELISA
Human Total MMP-8 ELISA Standard Curve

Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.

Simple Plex Human Total MMP-8 assay kit for use on Ella instrument. Contains cartridge, Sample Diluent SD13, and wash buffer.

Applications: Simple Plex
(4)
Source: CHO
Accession #: NP_032637
Applications: EnzAct
R&D Systems Recombinant Proteins and Enzymes
Source: NS0
Applications: WB
R&D Systems Recombinant Proteins and Enzymes

Control for use with Human Total MMP-8 Simple Plex Assay Cartridge Kit

Applications: Simple Plex

Contains 4 membranes-2 spotted in duplicate with antibodies against 35 different proteases and 2 spotted in duplicate with antibodies against 32 different protease inhibitors

Potent MMP inhibitor

Alternate Names: SC 78080
Chemical Name: N-Hydroxy-1-(2-methoxyethyl)-4-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonyl]-4-piperidinecarboxamide hydrochloride
Purity: ≥98% (HPLC)
Potent MMP inhibitor
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