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mGluR8 Products

The Group III metabotropic glutamate receptors include mGluR4, 6, 7 and 8. These 7-transmembrane glycoproteins are negatively coupled to adenylate cyclase and expressed presynaptically throughout the brain. MGluR8 shows pronounced expression in the dentate gyrus and CA3 regions of the hippocampus, and is thought to play a role in memory formation.

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48 results for "mGluR8" in Products

48 results for "mGluR8" in Products

mGluR8 Products

The Group III metabotropic glutamate receptors include mGluR4, 6, 7 and 8. These 7-transmembrane glycoproteins are negatively coupled to adenylate cyclase and expressed presynaptically throughout the brain. MGluR8 shows pronounced expression in the dentate gyrus and CA3 regions of the hippocampus, and is thought to play a role in memory formation.

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Selective group III mGlu agonist

Positive allosteric modulator of mGlu7 and mGlu8 receptors; also NK1 antagonist; brain penetrant

Potent and highly selective group II mGlu agonist

Positive allosteric modulator of group I mGlu receptors

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