17 results for "mGluR8" in Products
mGluR8 Products
The Group III metabotropic glutamate receptors include mGluR4, 6, 7 and 8. These 7-transmembrane glycoproteins are negatively coupled to adenylate cyclase and expressed presynaptically throughout the brain. MGluR8 shows pronounced expression in the dentate gyrus and CA3 regions of the hippocampus, and is thought to play a role in memory formation.
Selective group III mGlu agonist
Potent and highly selective group II mGlu agonist
Potent and selective mGlu8a agonist
Potent group III mGlu antagonist
Positive allosteric modulator of mGlu7 and mGlu8 receptors; also NK1 antagonist; brain penetrant
Active metabolite of oxcarbazepine (Cat. No. 3864)
Positive allosteric modulator of group I mGlu receptors
Selective positive allosteric modulator of group III mGlu receptors