411 results for "LDLR" in Products
LDLR Products
LDLR (Low Density Lipoprotein Receptor) is a widely expressed cell surface scavenger receptor. LDLR binds ApoB and ApoE, the apolipoproteins of low- and very low-density lipoproteins (LDL and VLDL), respectively. Hepatocyte LDLR is responsible for endocytosis and clearing of most plasma LDL cholesterol. At the low pH of the endocytic vesicle, it dissociates, allowing degradation of LDL and recycling of LDLR to the cell surface. Lack of LDLR expression or function causes familial hypercholesterolemia (FH). The protease PCSK9 can also cause increased plasma cholesterol by promoting LDLR degradation rather than recycling to the cell surface.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #472413 |
| Applications: | Flow |
Simple Plex cartridges are custom built to fit your needs. Choose from over 350 assays spanning human, mouse, rat, and non-human primate. Just select your sample type, cartridge size (16, 32, or 72 samples), and add up to 8 analytes per cartridge.
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Block, ICC |
| Reactivity: | Human, Mouse, Rat, Bovine, Porcine |
| Details: | Mouse IgG2B Monoclonal Clone #C7 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +3 More |
![Western Blot: LDLR Antibody (C7) [NBP1-78159]](https://resources.bio-techne.com/images/products/LDL-R-Antibody-C7-Western-Blot-NBP1-78159-img0008.jpg "Western Blot: LDLR Antibody (C7) [NBP1-78159]")
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, IHC, Block, CyTOF-ready |
| Sensitivity: | 0.064 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.313 - 20 ng/mL (Cell Culture Supernates, Tissue Homogenates, Serum, EDTA Plasma, Heparin Plasma) |
| Sensitivity: | 10.3 pg/mL |
| Applications: | ELISA |
| Assay Range: | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, Heparin Plasma, Urine) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #472413 |
| Applications: | Flow |
| Source: | NS0 |
| Accession #: | Q59FQ1 |
| Applications: | Bind |
| Source: | NS0 |
| Accession #: | P01130 |
| Applications: | BA |
| Assay Range: | 125 - 8,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #263123 |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #472413 |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #472413 |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Canine, Bovine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Func, KO, +1 More |
![Knockout Validated: LDLR Antibody - BSA Free [NBP1-06709]](https://resources.bio-techne.com/images/products/LDLR-Antibody-Knockout-Validated-NBP1-06709-img0009.jpg "Western Blot: LDLR Antibody - BSA Free [NBP1-06709]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |