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Lactate Dehydrogenase A/LDHA: Small Molecules and Peptides

Lactate Dehydrogenase A is also known as LDHA, LDH5, and EC 1.1.1.27. It is one of five isoforms of the lactate dehydrogenase family. LDHA catalyzes the conversion of pyruvate into lactate under anaerobic conditions. It is also a key component in the altered glycolytic metabolism that is a feature of cancer cells.

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3 results for "Lactate Dehydrogenase A/LDHA Small Molecules and Peptides" in Products

3 results for "Lactate Dehydrogenase A/LDHA Small Molecules and Peptides" in Products

Lactate Dehydrogenase A/LDHA: Small Molecules and Peptides

Lactate Dehydrogenase A is also known as LDHA, LDH5, and EC 1.1.1.27. It is one of five isoforms of the lactate dehydrogenase family. LDHA catalyzes the conversion of pyruvate into lactate under anaerobic conditions. It is also a key component in the altered glycolytic metabolism that is a feature of cancer cells.

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Potent and selective LDHA inhibitor

Chemical Name: 3-[[3-[(Cyclopropylamino)sulfonyl]-7-(2,4-dimethoxy-5-pyrimidinyl)-4-quinolinyl]amino]-5-(3,5-difluorophenoxy)benzoic acid
Purity: ≥98% (HPLC)
Potent and selective LDHA inhibitor

Potent lactate dehydrogenase Degrader (PROTAC®)

Chemical Name: 2-(5-(Cyclopropylmethyl)-3-(3-(6-(13-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-13-oxotridecanamido)hex-1-yn-1-yl)phenyl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid
Purity: ≥98% (HPLC)
Potent lactate dehydrogenase Degrader (PROTAC®)

LDHA inhibitor

Chemical Name: Methyl 1-hydroxy-6-phenyl-4-(trifluoromethyl)-1H-indole-2-carboxylate
Purity: ≥98% (HPLC)
LDHA inhibitor
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