NHI 2

Tocris Bioscience, part of Bio-Techne | Catalog # 5363

LDHA inhibitor
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Key Product Details

Description

LDHA inhibitor

View all Lactate Dehydrogenase A/LDHA Inhibitors »

Product Description

NHI 2 is an LDHA inhibitor; reduces lactate production in HeLa cells. Inhibits cell growth of LPC006 and PANC-1 cells in vitro. Enhances the antiproliferative effects of Gemcitabine (Cat. No. 3259) on LPC006 and PANC-1 cells. Also inhibits ferroptosis.

Product Specifications

Molecular Weight

335.28

Formula

C17H12F3NO3

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

Methyl 1-hydroxy-6-phenyl-4-(trifluoromethyl)-1H-indole-2-carboxylate

CAS Number

1269802-97-2

PubChem ID

51355147

InChI Key

YPPFWRWCZNXINO-UHFFFAOYSA-N

SMILES

ON2C1=CC(C3=CC=CC=C3)=CC(C(F)(F)F)=C1C=C2C(OC)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 33.53 100
Ethanol 33.53 100

Preparing Stock Solutions for NHI 2

The following data is based on the product molecular weight 335.28

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.98 mL 14.91 mL 29.83 mL
5 mM 0.60 mL 2.98 mL 5.97 mL
10 mM 0.30 mL 1.49 mL 2.98 mL
50 mM 0.06 mL 0.30 mL 0.60 mL

Calculators

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Reconstitution Calculator

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Product Documents for NHI 2

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for NHI 2

For research use only

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