Integrin alpha V beta 6 Products
Integrin alpha V beta 6 (aVb6) is a heterodimeric adhesion protein that is exclusively expressed on subsets of epithelial cells, especially during development, after injury or inflammation, or on many carcinomas. Active aVb6 binds to the extracellular matrix proteins Fibronectin and Tenascin C as well as the TGF-beta latency-associated peptide (LAP). It cooperates with LTBP-1, Fibronectin, and PAR-1 to activate TGF-beta 1 or TGF-beta 3 from large latent complexes. aVb6 also plays a role in Treg development, tumor progression, and virus cellular entry.
138 results for "Integrin alpha V beta 6" in Products
138 results for "Integrin alpha V beta 6" in Products
Integrin alpha V beta 6 Products
Integrin alpha V beta 6 (aVb6) is a heterodimeric adhesion protein that is exclusively expressed on subsets of epithelial cells, especially during development, after injury or inflammation, or on many carcinomas. Active aVb6 binds to the extracellular matrix proteins Fibronectin and Tenascin C as well as the TGF-beta latency-associated peptide (LAP). It cooperates with LTBP-1, Fibronectin, and PAR-1 to activate TGF-beta 1 or TGF-beta 3 from large latent complexes. aVb6 also plays a role in Treg development, tumor progression, and virus cellular entry.
| Source: | CHO |
| Accession #: | NP_002201.1 (Integrin alpha V) & P18564 (Integrin beta 6) |
| Applications: | Bind |
| Reactivity: | Human |
| Details: | Rat IgG2A Monoclonal Clone #AvB6 53a.2 |
| Applications: | WB, ICC/IF, Flow, IP, CyTOF-ready, +1 More |
![Immunoprecipitation: Integrin alpha V beta 6 Antibody (AvB6 53a.2) - BSA Free [NBP2-50449]](https://resources.bio-techne.com/images/products/Integrin-alpha-V-+-beta-6-Antibody-AvB6-53a-2-Western-Blot-NBP2-50449-img0002.jpg "Immunoprecipitation: Integrin alpha V beta 6 Antibody (AvB6 53a.2) - BSA Free [NBP2-50449]")
| Source: | CHO |
| Accession #: | P43406 (Integrin alpha V) & Q9Z0T9 (Integrin beta 6) |
| Applications: | BA |
Fc Chimera
| Source: | HEK293 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | XP_017456512.1 (Integrin alpha V) & Q6AYF4 (Integrin beta 6 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Rat IgG2A Monoclonal Clone #7k |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +2 More |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #STX-100 |
| Applications: | ELISA, Flow, Func |
![Integrin alpha V beta 6 Antibody (STX-100) [CoraFluor™ 1] - (Research Grade Biosimilar)](https://resources.bio-techne.com/images/products/nbp3-28326cl1_human-integrin-alpha-v-beta-6-mab-stx-100-corafluor-1-24920251634267.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human |
| Details: | Rat IgG2a Kappa Monoclonal Clone #AvB6 53a.2 |
| Applications: | WB, ELISA, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Rat IgG2a Kappa Monoclonal Clone #AvB6 53a.2 |
| Applications: | WB, ELISA, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Rat IgG2A Monoclonal Clone #AvB6 53a.2 |
| Applications: | ICC/IF, Flow, IP, CyTOF-ready, Func |
| Reactivity: | Human |
| Details: | Rat IgG2A Monoclonal Clone #AvB6 53a.2 |
| Applications: | ICC/IF, Flow, IP, CyTOF-ready, Func |
![Integrin alpha V beta 6 Antibody (AvB6 53a.2) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp2-50449cl1_rat-integrin-alpha-v-beta-6-mab-avb6-53a-2-corafluor-1-81020251047514.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human |
| Details: | Rat IgG2A Monoclonal Clone #AvB6 53a.2 |
| Applications: | ICC/IF, Flow, IP, CyTOF-ready, Func |
| Reactivity: | Human |
| Details: | Rat IgG2A Monoclonal Clone #7k |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +2 More |
| Reactivity: | Human |
| Details: | Rat IgG2A Monoclonal Clone #7k |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +2 More |
| Reactivity: | Human |
| Details: | Rat IgG2A Monoclonal Clone #7k |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +2 More |
![Integrin alpha V beta 6 Antibody (7k) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp2-50448cl1_rat-integrin-alpha-v-beta-6-mab-7k-corafluor-1-810202510522221.png "Product Feature: CoraFluor Probes for TR-FRET")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #STX-100 |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #STX-100 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human, Mouse (Negative) |
| Details: | Rat IgG1 Monoclonal Clone #Av beta6 62ow.17 |
| Applications: | IHC, WB |
![Integrin alpha V beta 6 Antibody (Av beta6 62ow.17) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp2-50450cl1_rat-integrin-alpha-v-beta-6-mab-av-beta6-62ow-17-cl1-25920251114301.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human, Mouse (Negative) |
| Details: | Rat IgG1 Monoclonal Clone #Av beta6 62ow.17 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse (Negative) |
| Details: | Rat IgG1 Monoclonal Clone #Av beta6 62ow.17 |
| Applications: | IHC, WB |
Potent integrin inhibitor (αvβ3/αvβ6); also improves stem cell attachment in 3D cell culture scaffolds
| Purity: | ≥95% (HPLC) |
ανβ6 integrin inhibitor
| Chemical Name: | N-[1-Oxo-5-(2-pyridinylamino)pentyl]-O-(phenylmethyl)-L-seryl-3-(3,5-dichlorophenyl)-β-alanine hydrochloride |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Rat IgG2A Monoclonal Clone #AvB6 53a.2 |
| Applications: | ICC/IF, Flow, IP, CyTOF-ready, Func |
| Reactivity: | Human |
| Details: | Rat IgG2A Monoclonal Clone #AvB6 53a.2 |
| Applications: | ICC/IF, Flow, IP, CyTOF-ready, Func |
| Reactivity: | Human |
| Details: | Rat IgG2A Monoclonal Clone #AvB6 53a.2 |
| Applications: | ICC/IF, Flow, IP, CyTOF-ready, Func |