Integrin alpha V beta 6 Antibody (7k) - BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-50448
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
CyTOF-ready, ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Rat IgG2A Clone # 7k
Format
BSA Free
Concentration
1 mg/ml
Product Specifications
Immunogen
3T3b6, mouse fibroblast expressing human Integrin alpha V beta 6
Specificity
Does not bind mouse.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Description
Novus Biologicals Rat Integrin alpha V beta 6 Antibody (7k) - BSA Free (NBP2-50448) is a monoclonal antibody validated for use in IHC, WB, ELISA, Flow, ICC/IF and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
Applications for Integrin alpha V beta 6 Antibody (7k) - BSA Free
Application
Recommended Usage
ELISA
1:100 - 1:2000
Flow Cytometry
20ug/ml
Immunocytochemistry/ Immunofluorescence
1:10 - 1:500
Immunohistochemistry
1:100 - 1:250
Immunoprecipitation
10 ul per 100-500 ug protein lysate
Western Blot
1:100 - 1:2000
Application Notes
This antibody is Cytof ready. Positive control(s): HaCaT, BT474.
Formulation, Preparation, and Storage
Purification
Protein G purified
Formulation
PBS
Format
BSA Free
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: Integrin alpha V beta 6
Integrin alpha V beta 6 (aVb6) is a heterodimeric adhesion protein that is exclusively expressed on subsets of epithelial cells, especially during development, after injury or inflammation, or on many carcinomas. Active aVb6 binds to the extracellular matrix proteins Fibronectin and Tenascin C as well as the TGF-beta latency-associated peptide (LAP). It cooperates with LTBP-1, Fibronectin, and PAR-1 to activate TGF-beta 1 or TGF-beta 3 from large latent complexes. aVb6 also plays a role in Treg development, tumor progression, and virus cellular entry.
Alternate Names
CD51, integrin subunit alpha V, ITGAV, MSK8, VNRA, VTNR
Gene Symbol
ITGAV
Additional Integrin alpha V beta 6 Products
Product Documents for Integrin alpha V beta 6 Antibody (7k) - BSA Free
Product Specific Notices for Integrin alpha V beta 6 Antibody (7k) - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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