8 results for "Immunosuppressants Small Molecules and Peptides" in Products
Immunosuppressants: Small Molecules and Peptides
Immunosuppressants are compounds that suppress the immune system and are used to treat inflammatory and autoimmune conditions such as asthma, rheumatoid arthritis and multiple sclerosis. They are also used for the prevention and treatment of organ transplant rejection.
mTOR inhibitor; immunosuppressant
| Chemical Name: | (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone |
| Purity: | ≥98% (HPLC) |
Calcineurin inhibitor
| Alternate Names: | Ciclosporin A |
| Purity: | ≥98% (HPLC) |
Adrenal glucocorticoid; immunosuppressant
| Chemical Name: | 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione |
| Purity: | ≥98% (HPLC) |
Potent calcineurin inhibitor; immunosuppressant
| Alternate Names: | Tacrolimus,Fujimycin |
| Chemical Name: | (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)tetrone |
| Purity: | ≥98% (HPLC) |
Inosine monophosphatase dehydrogenase (IMPDH) inhibitor
| Chemical Name: | 6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid |
| Purity: | ≥98% (HPLC) |
Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive
| Chemical Name: | (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-3b,4,4a,6,6a,7a,7b,8b,9,10-Decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one |
| Purity: | ≥98% (HPLC) |
Inosine monophosphate dehydrogenase (IMPDH) inhibitor
| Chemical Name: | 6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid 2-(4-morpholinyl)ethyl ester |
| Purity: | ≥98% (HPLC) |
Inhibitor of DHODH; active metabolite of Leflunomide
| Alternate Names: | A77 1726 |
| Chemical Name: | 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide |
| Purity: | ≥98% (HPLC) |
