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6 results for "Estrogen and Related Receptor Antagonists Small Molecules and Peptides" in Products

Estrogen and Related Receptor Antagonists: Small Molecules and Peptides

Estrogen controls many cellular processes including growth, differentiation and function of the reproductive system. In females, estrogen's main targets are the ovaries, uterus, vagina and mammary glands. In the male, target organs are the testes, prostate and epididymis. Estrogen is also responsible for the growth and maintenance of the skeleton and the normal functioning of the cardiovascular and nervous systems.

Estrogen exerts most of its actions via estrogen receptors (ER). Estrogen ...

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Estrogen receptor antagonist

Alternate Names: Fulvestrant
Chemical Name: 7α,17β-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol
Purity: ≥98% (HPLC)
Estrogen receptor antagonist

Potent and selective G protein-coupled estrogen receptor (GPER) antagonist

Chemical Name: N-[2-Cyclohexyl-4-(1-methylethyl)phenyl]-4-methoxybenzenemethanamine hydrochloride
Purity: ≥98% (HPLC)
Potent and selective G protein-coupled estrogen receptor (GPER) antagonist

Selective ERβ antagonist

Chemical Name: 4-[2-Phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]phenol
Purity: ≥98% (HPLC)
Selective ERβ antagonist

Selective GPER antagonist

Chemical Name: (±)-(3aR*,4S*,9bS*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-8-(1-methylethyl)-3H-cyclopenta[c]quinoline
Purity: ≥98% (HPLC)
Selective GPER antagonist

ERα antagonist; also activates unfolded protein response; active in vivo

Chemical Name: 1,3-Dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-2H-indol-2-one
Purity: ≥98% (HPLC)
ERα antagonist; also activates unfolded protein response; active in vivo

Highly selective ERα antagonist

Chemical Name: 1,3-Bis(4-hydroxyphenyl)-4-methyl-5-[4-(2-piperidinylethoxy)phenol]-1H-pyrazole dihydrochloride
Purity: ≥98% (HPLC)
Highly selective ERα antagonist
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