DPPIV/CD26 Products
DPPIV/CD26 is a serine exopeptidase that is expressed as a noncovalent homodimer on the surface of epithelial cells, endothelial cells, and activated lymphocytes. It regulates multiple aspects of immune and endocrine function by cleaving Xaa-Pro or Xaa-Ala dipeptides from the N-terminus of a wide variety of chemokines (CCL4 and 5, CXCL6, 9, 10, 11, and 12), growth factors (GM-CSF, IL-3), and peptide hormones (Glucagon, Glucagon-like Peptides 1 and 2, GIP, GHRH, Procalcitonin, Neuropeptide Y, and Substance P).
DPPIV interacts in cis with Adenosine Deaminase on T cells, in trans with Caveolin-1 on antigen presenting cells, and it serves as a cell entry coreceptor for HIV and coronavirus. It provides costimulatory proliferation and activation signals to both CD4+ and CD8+ T cells. A soluble form of DPPIV can be proteolytically shed from adipocytes, leading to insulin resistance in adipocytes and skeletal muscle.
Products:
350 results for "DPPIV/CD26" in Products
350 results for "DPPIV/CD26" in Products
DPPIV/CD26 Products
DPPIV/CD26 is a serine exopeptidase that is expressed as a noncovalent homodimer on the surface of epithelial cells, endothelial cells, and activated lymphocytes. It regulates multiple aspects of immune and endocrine function by cleaving Xaa-Pro or Xaa-Ala dipeptides from the N-terminus of a wide variety of chemokines (CCL4 and 5, CXCL6, 9, 10, 11, and 12), growth factors (GM-CSF, IL-3), and peptide hormones (Glucagon, Glucagon-like Peptides 1 and 2, GIP, GHRH, Procalcitonin, Neuropeptide Y, and Substance P).
DPPIV interacts in cis with Adenosine Deaminase on T cells, in trans with Caveolin-1 on antigen presenting cells, and it serves as a cell entry coreceptor for HIV and coronavirus. It provides costimulatory proliferation and activation signals to both CD4+ and CD8+ T cells. A soluble form of DPPIV can be proteolytically shed from adipocytes, leading to insulin resistance in adipocytes and skeletal muscle.
Products:
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IHC, ICC |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IHC |
| Sensitivity: | 0.072 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.313 - 20 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva, Urine) |
| Source: | HEK293 |
| Accession #: | CAA43118.1 |
| Applications: | EnzAct |
| Applications: | Func |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #222113 |
| Applications: | WB, Flow, CyTOF-ready |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Human, Monkey, Primate |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunohistochemistry-Paraffin: DPPIV/CD26 Antibody - BSA Free [NB100-59021]](https://resources.bio-techne.com/images/products/DPPIV-CD26-Antibody---BSA-Free-Immunohistochemistry-Paraffin-NB100-59021-img0005.jpg "Immunohistochemistry-Paraffin: DPPIV/CD26 Antibody - BSA Free [NB100-59021]")
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #222113 |
| Applications: | Flow |
| Source: | HEK293 |
| Accession #: | CAA43118.1 |
| Applications: | BA, EnzAct |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI11D7 |
| Applications: | IHC, WB, ICC/IF, Flow |
![Western Blot: DPPIV/CD26 Antibody (OTI11D7) [NBP2-02154]](https://resources.bio-techne.com/images/products/DPPIV-CD26-Antibody-11D7-Western-Blot-NBP2-02154-img0011.jpg "Western Blot: DPPIV/CD26 Antibody (OTI11D7) [NBP2-02154]")
| Source: | NS0 |
| Accession #: | P28843 |
| Applications: | EnzAct |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #JM11-42 |
| Applications: | IHC, WB, ICC/IF, Flow, KO |
![Western Blot: DPPIV/CD26 Antibody (JM11-42) [NBP2-78791]](https://resources.bio-techne.com/images/products/DPPIV-CD26-Antibody-JM11-42-Western-Blot-NBP2-78791-img0007.jpg "Western Blot: DPPIV/CD26 Antibody (JM11-42) [NBP2-78791]")
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #155202 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ICC |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
