10 results for "Dopamine Transporter Inhibitors Small Molecules and Peptides" in Products
Dopamine Transporter Inhibitors: Small Molecules and Peptides
Dopamine transporters (DAT) are sodium- and chloride-dependent members of the solute carrier family 6 (SLC6) widely distributed throughout the brain in areas of dopaminergic activity, including the striatum and substantia nigra. They provide rapid clearance of dopamine, adrenalin and noradrenalin from the synaptic cleft, terminating the neurotransmitter signal.
Dopamine transporters can also mediate an outward efflux and it has been suggested that inward and outward transport are independently ...
Non-selective inhibitor of dopamine and noradrenalin transporters
| Chemical Name: | 1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent 5-HT uptake inhibitor; also inhibits dopamine and noradrenalin uptake
| Alternate Names: | Lu 19-005 |
| Chemical Name: | (1R,3S)-rel-3-(3,4-Dichlorophenyl)-2,3-dihydro-N-methyl-1H-inden-1-amine hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective DA uptake inhibitor; also σ ligand
| Chemical Name: | 1-[2-[Bis-(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent noradrenalin and dopamine uptake inhibitor. Antidepressant
| Chemical Name: | 1,2,3,4-Tetrahydro-2-methyl-4-phenyl-8-isoquinolinamine maleate |
| Purity: | ≥98% (HPLC) |
Potent 5-HT and NA reuptake inhibitor (SNRI); also blocks dopamine reuptake
| Chemical Name: | (+)-(S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)propanamine hydrochloride |
| Purity: | ≥98% (HPLC) |
High affinity dopamine uptake inhibitor
| Chemical Name: | (3-endo)-3-[Bis(4-fluorophenyl)methoxy]-8-butyl-8-azabicyclo[3.2.1]octane hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent inhibitor of vesicular monoamine transport
| Chemical Name: | (3R,11bR)-rel-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one |
| Purity: | ≥98% (HPLC) |
Potent and selective DA uptake inhibitor
| Chemical Name: | 1-(2-Diphenylmethoxyethyl)-4-(3-phenyl-2-propenyl)-piperazine dihydrochloride |
| Purity: | ≥98% (HPLC) |
Inhibitor of vesicular monoamine transport
| Chemical Name: | (3β,16β,17α,18β,20α)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester |
| Purity: | ≥98% (HPLC) |
σ2 antagonist. Also DAT inhibitor
| Alternate Names: | BW 234U |
| Chemical Name: | 9-[3-(cis-3,5-Dimethyl-1-piperazinyl)propyl]-9H-carbazole dihydrochloride |
| Purity: | ≥98% (HPLC) |
