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Dkk-1: Proteome Profiler Antibody Arrays

Dkk-1 (Dickkopf related protein 1) is a secreted antagonist of Wnt/beta-Catenin signaling. It interacts with LRP-6, and internalized complexes of Dkk-1/LRP-6/Kremen 2 can downregulate Wnt signaling. The balance between Wnt signaling and Dkk-1 inhibition is critical for bone formation and homeostasis. In addition, Dkk-1 can act as either a tumor suppressor or promoter of metastasis.

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3 results for "Dkk-1 Proteome Profiler Antibody Arrays" in Products

3 results for "Dkk-1 Proteome Profiler Antibody Arrays" in Products

Dkk-1: Proteome Profiler Antibody Arrays

Dkk-1 (Dickkopf related protein 1) is a secreted antagonist of Wnt/beta-Catenin signaling. It interacts with LRP-6, and internalized complexes of Dkk-1/LRP-6/Kremen 2 can downregulate Wnt signaling. The balance between Wnt signaling and Dkk-1 inhibition is critical for bone formation and homeostasis. In addition, Dkk-1 can act as either a tumor suppressor or promoter of metastasis.

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Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies

Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies

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