Cyr61/CCN1 Products
Cyr61, also known as IGFBP-10 and CCN1, is a 50 kDa matricellular glycoprotein that regulates the growth and adhesion of vascular endothelial cells, fibroblasts, and monocytes. Cyr61 induces VEGF upregulation, angiogenesis, and tumorigenesis through interactions with integrins alpha V beta 3, alpha V beta 5, alpha M beta 2, and alpha 6 beta 1. Cyr61 is cleaved by plasmin within its VWF domain which generates an N-terminal fragment that is not associated with the matrix but retains the ability to induce endothelial cell migration.
276 results for "Cyr61/CCN1" in Products
276 results for "Cyr61/CCN1" in Products
Cyr61/CCN1 Products
Cyr61, also known as IGFBP-10 and CCN1, is a 50 kDa matricellular glycoprotein that regulates the growth and adhesion of vascular endothelial cells, fibroblasts, and monocytes. Cyr61 induces VEGF upregulation, angiogenesis, and tumorigenesis through interactions with integrins alpha V beta 3, alpha V beta 5, alpha M beta 2, and alpha 6 beta 1. Cyr61 is cleaved by plasmin within its VWF domain which generates an N-terminal fragment that is not associated with the matrix but retains the ability to induce endothelial cell migration.
| Reactivity: | Human, Mouse, Rabbit |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, IP, Func, +2 More |
![Immunohistochemistry: Cyr61/CCN1 Antibody - BSA Free [NB100-356]](https://resources.bio-techne.com/images/products/Cyr61-CCN1-Antibody-Immunohistochemistry-NB100-356-img0007.jpg "Immunohistochemistry: Cyr61/CCN1 Antibody - BSA Free [NB100-356]")
| Sensitivity: | 3.8 pg/mL |
| Applications: | ELISA |
| Assay Range: | 39.1 - 2,500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Saliva, Human Milk) |
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Applications: | Ctrl, Simple Plex |
| Reactivity: | Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Simple Western, IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #365108 |
| Applications: | WB |
| Source: | CHO |
| Accession #: | O00622 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #466305 |
| Applications: | IHC |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Simple Western, ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #365108 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #3A7.1B8 |
| Applications: | IHC, WB |
![Western Blot: Cyr61/CCN1 Antibody (3A7.1B8)Azide and BSA Free [NBP2-80685]](https://resources.bio-techne.com/images/products/Cyr61-CCN1-Antibody-3A7-1B8-Azide-and-BSA-Free-Western-Blot-NBP2-80685-img0001.jpg "Western Blot: Cyr61/CCN1 Antibody (3A7.1B8)Azide and BSA Free [NBP2-80685]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #3A7.1B8 |
| Applications: | IHC, WB |
![Western Blot: Cyr61/CCN1 Antibody (3A7.1B8)BSA Free [NBP2-36490]](https://resources.bio-techne.com/images/products/Cyr61-CCN1-Antibody-3A7-1B8-Western-Blot-NBP2-36490-img0004.jpg "Western Blot: Cyr61/CCN1 Antibody (3A7.1B8)BSA Free [NBP2-36490]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #HL2144 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #434311 |
| Applications: | ELISA |
