CCL3/MIP-1 alpha Products
CCL3/MIP-1 alpha, is a beta chemokine that can be induced in a variety of hematopoietic cells, fibroblasts, smooth muscle cells, and epithelial cells. It forms complexes with sulfated proteoglycans and also associates into noncovalently-linked dimers and high molecular weight polymers. These complexes of CCL3 are protected from proteolytic digestion by insulin degrading enzyme (IDE) which can cleave the monomeric chemokine. CCL3 signals through CCR1, CCR3, and CCR5, and it is internalized by the decoy chemokine receptor D6. CCL3 promotes the chemoattraction, adhesion to activated vascular endothelium, and cellular activation of many hematopoietic cell types. It can promote tumor metastasis, hyperalgesia, and inflammation and suppress HIV replication and hematopoietic stem cell proliferation.
511 results for "CCL3/MIP-1 alpha" in Products
511 results for "CCL3/MIP-1 alpha" in Products
CCL3/MIP-1 alpha Products
CCL3/MIP-1 alpha, is a beta chemokine that can be induced in a variety of hematopoietic cells, fibroblasts, smooth muscle cells, and epithelial cells. It forms complexes with sulfated proteoglycans and also associates into noncovalently-linked dimers and high molecular weight polymers. These complexes of CCL3 are protected from proteolytic digestion by insulin degrading enzyme (IDE) which can cleave the monomeric chemokine. CCL3 signals through CCR1, CCR3, and CCR5, and it is internalized by the decoy chemokine receptor D6. CCL3 promotes the chemoattraction, adhesion to activated vascular endothelium, and cellular activation of many hematopoietic cell types. It can promote tumor metastasis, hyperalgesia, and inflammation and suppress HIV replication and hematopoietic stem cell proliferation.
| Sensitivity: | 1.5 pg/mL |
| Applications: | ELISA |
| Assay Range: | 4.7 - 300 pg/mL (Cell Culture Supernates, Serum) |
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Sensitivity: | 10 pg/mL |
| Applications: | ELISA |
| Assay Range: |
31.2 - 1,000 pg/mL (Cell Culture Supernates) 46.9 - 1,500 pg/mL (Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Assay Range: | 7.81 - 500 pg/mL |
| Applications: | ELISA |
| Assay Range: | 7.81 - 500 pg/mL |
| Applications: | ELISA |
| Source: | E. coli |
| Accession #: | P10147 |
| Applications: | BA, BA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ICC, Neut |
| Source: | E. coli |
| Accession #: | Q5QNW0 |
| Applications: | BA, BA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #39624 |
| Applications: | WB, Flow |
| Applications: | Ctrl, Simple Plex |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #39624 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #14215 |
| Applications: | ELISA, Neut |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Reactivity: | Rat |
| Details: | Mouse IgG1 Monoclonal Clone #769324 |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #93342 |
| Applications: | ICFlow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #39624 |
| Applications: | ICFlow |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Reactivity: | Cotton Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #756613 |
| Applications: | WB, ICC |
