c-Myc: Small Molecules and Peptides
Human c-Myc is a 439 amino acid transcription factor with a bHLH/LZ (basic Helix-Loop-Helix, Leucine Zipper) domain. c-Myc DNA-binding and transcription function is achieved upon heterodimerization with its partner Max. c-Myc is often over-expressed and mutated in hematopoietic tumors. Mutations in c-Myc frequently result in truncations that remove the transactivation region or in the bHLH/LZ domain required for association with Max and DNA.
4 results for "c-Myc Small Molecules and Peptides" in Products
4 results for "c-Myc Small Molecules and Peptides" in Products
c-Myc: Small Molecules and Peptides
Human c-Myc is a 439 amino acid transcription factor with a bHLH/LZ (basic Helix-Loop-Helix, Leucine Zipper) domain. c-Myc DNA-binding and transcription function is achieved upon heterodimerization with its partner Max. c-Myc is often over-expressed and mutated in hematopoietic tumors. Mutations in c-Myc frequently result in truncations that remove the transactivation region or in the bHLH/LZ domain required for association with Max and DNA.
Selective USP25 and USP28 inhibitor
| Chemical Name: | 2-[[[5-Bromo-2-[[4-fluoro-3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]amino]ethanol |
| Purity: | ≥98% (HPLC) |
Inhibits c-Myc-Max dimerization
| Chemical Name: | 5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone |
| Purity: | ≥98% (HPLC) |
Selective p300/CBP bromodomain inhibitor
| Chemical Name: | (6S)-1-(3,4-Difluorophenyl)-6-[5-(3,5-dimethyl-4-isoxazolyl)-1-(trans-4-methoxycyclohexyl)-1H-benzimidazol-2-yl]-2-piperidinone |
| Purity: | ≥98% (HPLC) |
High affinity Myc inhibitor
| Chemical Name: | 4-[2-(2-Furanyl)-6-(4-nitrophenyl)-4-pyridinyl]benzamide |
| Purity: | ≥98% (HPLC) |
