BMP-2 Products
BMP-2 (Bone morphogenetic protein 2) is a TGF-beta superfamily cytokine that plays a dominant role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. BMP-2 forms disulfide linked homodimers and heterodimers with BMP-7. BMP-2 signals through heterodimeric complexes of type I receptors (ActiRI, BMPR-IA, or BMPR-IB) and type II receptors (BMP RII or ActRIIB).
It induces chondrocyte proliferation, endochondral bone formation, longitudinal bone growth, and bone and cartilage repair. BMP-2/BMP-7 heterodimers are significantly more potent than BMP-2 homodimers at inducing bone formation in vivo. BMP-2 also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells, and is required for cardiac contractility.
Products:
229 results for "BMP-2" in Products
229 results for "BMP-2" in Products
BMP-2 Products
BMP-2 (Bone morphogenetic protein 2) is a TGF-beta superfamily cytokine that plays a dominant role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. BMP-2 forms disulfide linked homodimers and heterodimers with BMP-7. BMP-2 signals through heterodimeric complexes of type I receptors (ActiRI, BMPR-IA, or BMPR-IB) and type II receptors (BMP RII or ActRIIB).
It induces chondrocyte proliferation, endochondral bone formation, longitudinal bone growth, and bone and cartilage repair. BMP-2/BMP-7 heterodimers are significantly more potent than BMP-2 homodimers at inducing bone formation in vivo. BMP-2 also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells, and is required for cardiac contractility.
Products:
| Sensitivity: | 29 pg/mL |
| Applications: | ELISA |
| Assay Range: | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Bone Extracts) |
| Reactivity: | Human, Mouse, Rat, Canine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
Simple Plex Human BMP-2 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Source: | E. coli |
| Accession #: | P12643 |
| Applications: | BA |
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
| Applications: | Simple Plex |
| Assay Range: | 46.9 - 3,000 pg/mL |
| Applications: | ELISA |
| Source: | CHO |
| Accession #: | P12643 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | P12643.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | NP_001191 (BMP-2) & NP_001710 (BMP-7) |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #100230 |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #100221 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
For use with catalog numbers DBP200, SBP200, PDBP200
| Applications: | Ctrl |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #65529 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #253717 |
| Applications: | WB, IHC |
| Source: | E. coli |
| Accession #: | P12643 (BMP-2) & P22004 (BMP-6) |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #100221 |
| Applications: | WB, ELISA(Cap), ELISA(Det) |
| Reactivity: | Zebrafish |
| Details: | Mouse IgG1 Monoclonal Clone #208301 |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #369505 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #100230 |
| Reactivity: | Zebrafish |
| Details: | Mouse IgG1 Monoclonal Clone #169125 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #9E10G12 |
| Applications: | WB, ELISA, ICC/IF, Flow |
![Western Blot: BMP-2 Antibody (9E10G12)BSA Free [NBP2-52422]](https://resources.bio-techne.com/images/products/BMP-2-Antibody-9E10G12-Western-Blot-NBP2-52422-img0003.jpg "Western Blot: BMP-2 Antibody (9E10G12)BSA Free [NBP2-52422]")
| Applications: | ELISA |
Control for use with Human BMP-2 Simple Plex Cartridge Kit
| Applications: | Ctrl, Simple Plex |