BMP-2: Simple Plex
BMP-2 (Bone morphogenetic protein 2) is a TGF-beta superfamily cytokine that plays a dominant role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. BMP-2 forms disulfide linked homodimers and heterodimers with BMP-7. BMP-2 signals through heterodimeric complexes of type I receptors (ActiRI, BMPR-IA, or BMPR-IB) and type II receptors (BMP RII or ActRIIB).
It induces chondrocyte proliferation, endochondral bone formation, longitudinal bone growth, and bone and cartilage repair. BMP-2/BMP-7 heterodimers are significantly more potent than BMP-2 homodimers at inducing bone formation in vivo. BMP-2 also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells, and is required for cardiac contractility.
Products:
3 results for "BMP-2 Simple Plex" in Products
3 results for "BMP-2 Simple Plex" in Products
BMP-2: Simple Plex
BMP-2 (Bone morphogenetic protein 2) is a TGF-beta superfamily cytokine that plays a dominant role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. BMP-2 forms disulfide linked homodimers and heterodimers with BMP-7. BMP-2 signals through heterodimeric complexes of type I receptors (ActiRI, BMPR-IA, or BMPR-IB) and type II receptors (BMP RII or ActRIIB).
It induces chondrocyte proliferation, endochondral bone formation, longitudinal bone growth, and bone and cartilage repair. BMP-2/BMP-7 heterodimers are significantly more potent than BMP-2 homodimers at inducing bone formation in vivo. BMP-2 also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells, and is required for cardiac contractility.
Products:
Simple Plex Human BMP-2 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
| Applications: | Simple Plex |
Control for use with Human BMP-2 Simple Plex Cartridge Kit
| Applications: | Ctrl, Simple Plex |