beta-1 Adrenergic R/ADRB1: Small Molecules and Peptides
The beta-1 Adrenergic Receptor (ADRB1) belongs to the G protein-coupled receptor 1 family. The adrenergic receptors, including ADRB1, are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. ADRB1 binds epinephrine and norepinephrine with approximately equal affinity. ADRB1 is localized at the plasma membrane. It is also found in the Golgi upon Golgi-associated PDZ and coiled-coil motif-containing protein (GOPC) overexpression. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.
9 results for "beta-1 Adrenergic R/ADRB1 Small Molecules and Peptides" in Products
9 results for "beta-1 Adrenergic R/ADRB1 Small Molecules and Peptides" in Products
beta-1 Adrenergic R/ADRB1: Small Molecules and Peptides
The beta-1 Adrenergic Receptor (ADRB1) belongs to the G protein-coupled receptor 1 family. The adrenergic receptors, including ADRB1, are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. ADRB1 binds epinephrine and norepinephrine with approximately equal affinity. ADRB1 is localized at the plasma membrane. It is also found in the Golgi upon Golgi-associated PDZ and coiled-coil motif-containing protein (GOPC) overexpression. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.
| Alternate Names: | Isoprenaline |
| Chemical Name: | 4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,2-benzenediol hydrochloride |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | (RS)-1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochloride |
| Chemical Name: | 4-[3-[tert-Butylamino]-2-hydroxypropoxy]-1H-indole-2-carbonitrile hemifumarate |
| Purity: | ≥98% (HPLC) |
| Alternate Names: | BM 14190 |
| Chemical Name: | 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 1-[2-((3-Carbamoyl-4-hydroxy)phenoxy)ethylamino]-3-[4-(1-methyl-4-trifluoromethyl-2-imidazolyl)phenoxy]-2-propanol dihydrochloride |
| Purity: | ≥96% (HPLC) |
| Chemical Name: | 4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]aminoethyl-1,2-benzenediol hydrochloride |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | (±)-[2R*(1S*5S*(S*))]-α,α'-[Iminobis(methylene)bis(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol) |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol hemitartrate |
| Purity: | ≥98% (HPLC) |
| Alternate Names: | ICI 118,587 |
| Chemical Name: | 1-(4-Hydroxyphenoxy)-3-[2-(4-morpholinocarboxamido)ethylamino]-2-propanol hemifumarate |
| Purity: | ≥97% (HPLC) |
