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173 results for "Bcl-xL" in Products

Bcl-xL Products

Bcl-x is a member of the Bcl-2 family of proteins that regulates outer mitochondrial membrane permeability. Alternative splicing results in two distinct Bcl-x isoforms. Bcl-xL (long) is an anti-apoptotic protein that prevents release of Cytochromec from the mitochondrial intermembrane space into the cytosol. Bcl-xs (short) is a pro-apoptotic member that can initiate programmed cell death.

Blue-fluorescent dye for DNA staining. Cell permeable. Used for: nuclear counterstain, apoptosis analysis, fixed and live-cell staining. Application: flow cytometry, confocal microscopy

Chemical Name: 2'-(4-Ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-1H-benzimidazole trihydrochloride
Applications: Flow
Purity: ≥98% (HPLC)
Fluorescent dye for staining DNA

Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies

R&D Systems Proteome Profiler Antibody Array Kits

Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines

Chemical Name: 4-[4-[(4'-Chloro[1,1'-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide
Purity: ≥97% (HPLC)
Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines

Potent and selective Bcl-xL inhibitor; antitumor and inducer of apoptosis

Chemical Name: 6-[8-[(2-Benzothiazolylamino)carbonyl]-3,4-dihydro-2(1H)-isoquinolinyl]-3-[5-methyl-1-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1H-pyrazol-4-yl]-2-pyridinecarboxylic acid
Purity: ≥98% (HPLC)
Potent and selective Bcl-xL inhibitor; antitumor and inducer of apoptosis

High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor

Chemical Name: 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide
Purity: ≥98% (HPLC)
High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor
Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #2052A
Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #2052A
Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #2052A

Cell-permeable protein kinase C inhibitor

Chemical Name: 1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium chloride
Purity: ≥98% (HPLC)
Cell-permeable protein kinase C inhibitor

Inhibitor of Bcl-2 family members; antiapoptotic

Alternate Names: GX15-070
Chemical Name: 2-[2-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene)-3-methoxy-2H-pyrrol-5-yl]-1H-indole methanesulfonate
Purity: ≥98% (HPLC)
Inhibitor of Bcl-2 family members; antiapoptotic
Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #2052A
Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #2052A
Assay Range: 625 - 20,000 pg/mL
Applications: ELISA
(3)
Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #2052A
Source: E. coli
Accession #: Q64373
Applications: InhibAct
R&D Systems Recombinant Proteins and Enzymes
Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC, WB
Western Blot: Bcl-xL Antibody [NBP2-38262]
(2)
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