APJ: Small Molecules and Peptides
APJ is a G-protein coupled receptor that is related to the angiotensin receptor. It is primarily expressed in coronary artery endothelium and binds the endogenous ligand, apelin. Apelin signaling through APJ was found to be essential for normal vascular development in frog embryo. APJ can also function as a co-receptor for HIV. APJ and apelin have been shown to be involved in the differentiation of embryonic stem cells toward cardiac lineage.
5 results for "APJ Small Molecules and Peptides" in Products
5 results for "APJ Small Molecules and Peptides" in Products
APJ: Small Molecules and Peptides
APJ is a G-protein coupled receptor that is related to the angiotensin receptor. It is primarily expressed in coronary artery endothelium and binds the endogenous ligand, apelin. Apelin signaling through APJ was found to be essential for normal vascular development in frog embryo. APJ can also function as a co-receptor for HIV. APJ and apelin have been shown to be involved in the differentiation of embryonic stem cells toward cardiac lineage.
Endogenous apelin agonist
| Purity: | ≥95% (HPLC) |
Potent apelin antagonist
| Purity: | ≥95% (HPLC) |
Potent peptide apelin agonist
| Alternate Names: | [pGlu1]-Apelin-13 |
| Purity: | ≥95% (HPLC) |
Non-peptide apelin agonist
| Chemical Name: | (E)-4-Methyl-5-(((phenylsulfonyl)oxy)imino)-[1,1'-bi(cyclohexane)]-3,6-dien-2-one |
| Purity: | ≥98% (HPLC) |
Apelin antagonist
| Chemical Name: | 5-[(4-Nitrobenzoyl)oxy]-2-[(2-pyrimidinylthio)methyl]-4H-pyran-4-one |
| Purity: | ≥98% (HPLC) |
