AMPK alpha 2 Products
AMP-activated protein kinase (AMPK) is a heterotrimeric complex consisting of a catalytic a subunit and regulatory beta and gamma subunits. Each subunit exists as alternate isoforms (alpha 1, alpha 2, beta 1, beta 2, gamma 1, gamma 2, gamma 3), with all 12 combinations capable of forming complexes. The catalytic a subunit of AMPK is activated allosterically by AMP and by phosphorylation via the AMPK kinase LKB1. Active AMPK downregulates anabolic pathways such as fatty acid, triglyceride, and cholesterol synthesis, and up-regulates catabolic pathways such as glycolysis and fatty acid oxidation. AMPK's role in metabolic regulation has implicated this serine/threonine kinase as a therapeutic target in heart disease, obesity, and diabetes.
120 results for "AMPK alpha 2" in Products
120 results for "AMPK alpha 2" in Products
AMPK alpha 2 Products
AMP-activated protein kinase (AMPK) is a heterotrimeric complex consisting of a catalytic a subunit and regulatory beta and gamma subunits. Each subunit exists as alternate isoforms (alpha 1, alpha 2, beta 1, beta 2, gamma 1, gamma 2, gamma 3), with all 12 combinations capable of forming complexes. The catalytic a subunit of AMPK is activated allosterically by AMP and by phosphorylation via the AMPK kinase LKB1. Active AMPK downregulates anabolic pathways such as fatty acid, triglyceride, and cholesterol synthesis, and up-regulates catabolic pathways such as glycolysis and fatty acid oxidation. AMPK's role in metabolic regulation has implicated this serine/threonine kinase as a therapeutic target in heart disease, obesity, and diabetes.
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IHC, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #847123 |
| Applications: | WB, Simple Western, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #847123 |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #847123 |
| Applications: | WB, ICC |
| Reactivity: | Human, Monkey |
| Details: | Mouse IgG1 Monoclonal Clone #8E11H5 |
| Applications: | IHC, WB, ELISA, Flow |
![Western Blot: AMPK alpha 2 Antibody (8E11H5)BSA Free [NBP2-61852]](https://resources.bio-techne.com/images/products/AMPK-alpha-2-Antibody-8E11H5-Western-Blot-NBP2-61852-img0006.jpg "Western Blot: AMPK alpha 2 Antibody (8E11H5)BSA Free [NBP2-61852]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
![Western Blot: AMPK alpha 2 Antibody [NB100-238]](https://resources.bio-techne.com/images/products/AMPK-alpha-2-Antibody-Western-Blot-NB100-238-img0005.jpg "Western Blot: AMPK alpha 2 Antibody [NB100-238]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #847123 |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #847123 |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #847123 |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #847123 |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #847123 |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #847123 |
| Applications: | WB, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ICC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: AMPK alpha 2 Antibody [NBP2-38532]](https://resources.bio-techne.com/images/products/AMPK-alpha-2-Antibody-Western-Blot-NBP2-38532-img0002.jpg "Western Blot: AMPK alpha 2 Antibody [NBP2-38532]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #1G8 |
| Applications: | WB, ELISA, ICC/IF, Func, Mycoplasma |
![Western Blot: AMPK alpha 2 Antibody (1G8) [H00005563-M02]](https://resources.bio-techne.com/images/products/AMPK-alpha-2-Antibody-1G8-Western-Blot-H00005563-M02-img0009.jpg "Western Blot: AMPK alpha 2 Antibody (1G8) [H00005563-M02]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #5B4G1 |
| Applications: | IHC, WB, ELISA |
![Western Blot: AMPK alpha 2 Antibody (5B4G1)BSA Free [NBP2-61853]](https://resources.bio-techne.com/images/products/AMPK-alpha-2-Antibody-5B4G1-Western-Blot-NBP2-61853-img0004.jpg "Western Blot: AMPK alpha 2 Antibody (5B4G1)BSA Free [NBP2-61853]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: AMPK alpha 2 Antibody [NBP1-49859]](https://resources.bio-techne.com/images/products/AMPK-alpha-2-Antibody-Western-Blot-NBP1-49859-img0005.jpg "Western Blot: AMPK alpha 2 Antibody [NBP1-49859]")