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61 results for "5-HT7" in Products

5-HT7 Products

The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. This isoform (A) is the predominant isoform in spleen, caudate and hippocampus. 5-HT7 isoform B is expressed at lower levels. 5-HT7 belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Pharmacological and genetic tools targeting 5-HT7 in preclinical animal models have implicated this receptor in diverse (patho)physiological processes of the central nervous system (CNS).

Reactivity: Human, Mouse, Rat, Canine
Details: Rabbit IgG Polyclonal
Applications: WB, ICC/IF, Flow, Simple Western
Western Blot: 5-HT7 Antibody [NB100-56352]
(4)

Endogenous 5-HT receptor agonist

Alternate Names: 5-Hydroxytryptamine,5-HT
Chemical Name: 3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride
Purity: ≥98% (HPLC)
Endogenous 5-HT receptor agonist

5-HT1 agonist; also has high affinity for 5-ht5a and 5-HT7

Alternate Names: AH-21467,5-CT
Purity: ≥99% (HPLC)
5-HT1 agonist; also has high affinity for 5-ht5a and 5-HT7

Potent and selective 5-HT7 antagonist; brain penetrant

Chemical Name: (2R)-1-[(3-Hydroxyphenyl)sulfonyl]-2-[2-(4-methyl-1-piperidinyl)ethyl]pyrrolidine hydrochloride
Purity: ≥98% (HPLC)
Potent and selective 5-HT7 antagonist; brain penetrant

High affinity and selective 5-HT7 antagonist; orally bioavailable

Chemical Name: 6-Chloro-2a-[4-[4-(4-chlorophenyl)-3,6-dihydro-1(2H)-pyridinyl]butyl]-2a,3,4,5-tetrahydrobenz[cd]indol-2(1H)-one hydrochloride
Purity: ≥98% (HPLC)
High affinity and selective 5-HT7 antagonist; orally bioavailable

Potent 5-HT7 agonist

Chemical Name: (2S)-5-(1,3,5-Trimethylpyrazol-4-yl)-2-(dimethylamino)tetralin
Purity: ≥98% (HPLC)
Potent 5-HT7 agonist
Reactivity: Human
Details: Mouse IgG2b Monoclonal Clone #1015322
Applications: Flow, IHC, CyTOF-ready
5-HT7 Antibody (1015322) [Allophycocyanin]

Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant

Alternate Names: Org 3770,6-Azamianserin
Chemical Name: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
Purity: ≥98% (HPLC)
Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant
Reactivity: Human, Mouse, Rat, Guinea Pig
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF
Immunohistochemistry-Paraffin: 5-HT7 Antibody [NBP1-46598]
(2)
Reactivity: Human
Details: Mouse IgG2b Monoclonal Clone #1015322
Applications: Flow, IHC, CyTOF-ready
Detection of 5-HT7 antibody in HEK293 Human Cell Line Transfected with Human 5-HT7 and eGFP antibody by Flow Cytometry.
(2)

Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent

Chemical Name: (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate
Purity: ≥98% (HPLC)
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent

Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #4E6D2
Applications: IHC, WB, ICC/IF
Western Blot: 5-HT7 Antibody (4E6D2) [NBP3-15870]
(3)
Reactivity: Human
Details: Mouse IgG2a Monoclonal Clone #1015322
Applications: Flow
Reactivity: Human
Details: Mouse IgG2a Monoclonal Clone #1015322
Applications: Flow
Reactivity: Human
Details: Mouse IgG2b Monoclonal Clone #1015322
Reactivity: Human
Details: Mouse IgG2b Monoclonal Clone #1015322
Reactivity: Human
Details: Mouse IgG2a Monoclonal Clone #1015322
Applications: Flow
Reactivity: Human
Details: Mouse IgG2b Monoclonal Clone #1015322
Reactivity: Human
Details: Mouse IgG2b Monoclonal Clone #1015322
Reactivity: Human
Details: Mouse IgG2a Monoclonal Clone #1015322
Applications: Flow
Reactivity: Human
Details: Mouse IgG2a Monoclonal Clone #1015322
Applications: Flow
Reactivity: Human
Details: Mouse IgG2a Monoclonal Clone #1015322
Applications: Flow
Reactivity: Human
Details: Mouse IgG2b Monoclonal Clone #1015322
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