5-Carboxamidotryptamine maleate

Name: 5-Carboxamidotryptamine maleate
Brand: Tocris Bioscience
SKU: 0458

Tocris Bioscience, part of Bio-Techne | Catalog # 0458

Citations (32)

COA / SDS

5-HT1 agonist; also has high affinity for 5-ht5a and 5-HT7

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Product Description
Product Specifications
Solubility
Preparing Stock Solutions
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

5-HT1 agonist; also has high affinity for 5-ht5a and 5-HT7

Alternative Names

AH-21467,5-CT

View all Non-selective 5-HT1 Receptor Agonists »

Product Description

5-Carboxamidotryptamine maleate is a 5-HT₁ agonist with high affinity at 5-HT_1A, 5-HT_1B , 5-HT_1D, 5-ht₅ and 5-HT₇ receptors.

Product Specifications

Molecular Weight

319.32

Formula

C₁₁H₁₃N₃O.C₄H₄O₄

Storage

Store at +4°C

Purity

≥99% (HPLC)

CAS Number

74885-72-6

PubChem ID

11709509

InChI Key

PZQZSWAOVAMBQM-BTJKTKAUSA-N

SMILES

OC(=O)\C=C/C(O)=O.NCCC1=CNC2=CC=C(C=C12)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	31.93	100

Preparing Stock Solutions for 5-Carboxamidotryptamine maleate

The following data is based on the product molecular weight 319.32

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.13 mL	15.66 mL	31.32 mL
5 mM	0.63 mL	3.13 mL	6.26 mL
10 mM	0.31 mL	1.57 mL	3.13 mL
50 mM	0.06 mL	0.31 mL	0.63 mL

Calculators

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

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Reconstitution Calculator

Background References

References are publications that support the biological activity of the product.

Wood Antagonist activity of meta-chlorophenylpiperazine and partial agonist activity of 8-OH-DPAT at the 5-HT₇ receptor. Eur.J.Pharmacol. 2000 PMID: 10822046
Nowak [³H]-5-carboxamidotryptamine labels 5HT_1D binding sites in bovine substantia nigra. Br.J.Pharmacol. 1993 PMID: 8401931
Zifa and Fillion 5-Hydroxytryptamine receptors. Pharmacol.Rev. 1992 PMID: 1359584
Beer An investigation of the 5-HT_1D receptor binding affinity of 5-hydroxytryptamine, 5-carboxyamidotryptamine and sumatr. in the central nervous system of seven species. Eur.J.Pharmacol. 1992 PMID: 1325915