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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

CoraFluor 1

Antibody Source

Monoclonal Mouse IgG2B Clone # 293106

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human LILRA3/CD85e
Arg18-Glu439
Accession # Q8N6C8

Specificity

Detects human LILRA3/CD85e in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) ILT1, 2, 3, 4, 5, rhLIR6, or rhLIR8 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(TM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

CoraFluor(TM) 1, amine reactive

CoraFluor(TM) 1, thiol reactive

For more information, please see our CoraFluor(TM) TR-FRET technology flyer.

Applications for ILT6/CD85e/LILRA3 Antibody (293106) [CoraFluor™ 1]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: LILRA3/CD85e

LILRA3, also known as Leukocyte immunoglobulin-like receptor subfamily A member 3, has 3 isoforms, a 439 amino acid isoform that is 47 kDa, a 375 amino acid isoform that is 40 kDa, and a 456 amino acid isoform that is 49; detected in B-cells, and at lower levels in natural killer (NK) cells, and in peripheral blood monocytes and lung; lacks a transmembrane region and is presumed to be a soluble receptor and may act as soluble receptor for class I MHC antigens. Studies on this protein have shown relationship with the following diseases and disorders: multiple sclerosis, rheumatoid arthritis, arthritis, ascariasis, trichuriasis, multiple sclerosis, rheumatism, interferon, and hepatitis c. This protein has been shown to interact with EWSR1 and USP46 proteins in osteoclast differentiation, defense response, and signal transduction pathways.

Long Name

Leukocyte Immunoglobulin-like Receptor, Subfamily A (with TM and ITIM Domains), Member 3

Alternate Names

CD85e, HM31, HM43, ILT6, LIR4

Gene Symbol

LILRA3

Additional LILRA3/CD85e Products

Product Documents for ILT6/CD85e/LILRA3 Antibody (293106) [CoraFluor™ 1]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ILT6/CD85e/LILRA3 Antibody (293106) [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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