Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD94 PE-conjugated Monoclonal Antibody (Catalog # FAB1058P) and Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal Antibody (Catalog # FAB2408A). Quadrant markers were set based on control antibody staining (Catalog # IC002P). View our protocol for Staining Membrane-associated Proteins.

Applications for Human CD94 PE-conjugated Antibody

Application

Recommended Usage

Flow Cytometry

10 µL/10⁶ cells
Sample: Human peripheral blood mononuclear cells (PBMCs)

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

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Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: CD94

CD94, also known as KLAD1, is a 30 kDa type II transmembrane protein with an extracellular C-type lectin domain. It is expressed by natural killer (NK) cells and a subset of CD8⁺ T cells, with cellular activation resulting in increased cell surface expression. Although CD94 can occur as a non-signaling homodimer, functional activity occurs when CD94 exists as a heterodimer with an NKG2 family member. A CD94/NKG2A heterodimer delivers an inhibitory signal to the expressing cell, whereas, a CD94/NKG2C heterodimer associates with the DAP12 adapter protein and delivers an activating signal. Both heterodimeric complexes recognize HLA-E with an associated peptide derived from the signal peptide of other HLA proteins.

Alternate Names

CD94, KLRD1

Entrez Gene IDs

3824 (Human); 16643 (Mouse); 102119829 (Cynomolgus Monkey)

Gene Symbol

KLRD1

Additional CD94 Products

Product Documents for Human CD94 PE-conjugated Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Human CD94 PE-conjugated Antibody

For research use only

Citations
Reviews

Human CD94 PE-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB1058P

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

View all CD94 Antibodies »

Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Scientific Data Images for Human CD94 PE-conjugated Antibody

Detection of CD94 in Human PBMCs by Flow Cytometry.

Applications for Human CD94 PE-conjugated Antibody

Flow Cytometry

Spectra Viewer

Plan Your Experiments

Formulation, Preparation, and Storage

Purification

Formulation

Shipping

Stability & Storage

Background: CD94

Alternate Names

Entrez Gene IDs

Gene Symbol

Additional CD94 Products

Product Documents for Human CD94 PE-conjugated Antibody

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for Human CD94 PE-conjugated Antibody

CONTACT INFORMATION

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