XPB: Small Molecules and Peptides
The XP (Xeroderma Pigmentosum) family is made up of seven genes, XPA-XPG, involved in nucleotide excision repair (ER). Mutations can result in XP, an autosomal recessive genetic disorder characterized by extreme sensitivity to ultraviolet light and a predisposition to skin cancer. XP variant (XPV) is a form of XP caused by mutation in the DNA polymerase eta (POLH) gene.
1 result for "XPB Small Molecules and Peptides" in Products
1 result for "XPB Small Molecules and Peptides" in Products
XPB: Small Molecules and Peptides
The XP (Xeroderma Pigmentosum) family is made up of seven genes, XPA-XPG, involved in nucleotide excision repair (ER). Mutations can result in XP, an autosomal recessive genetic disorder characterized by extreme sensitivity to ultraviolet light and a predisposition to skin cancer. XP variant (XPV) is a form of XP caused by mutation in the DNA polymerase eta (POLH) gene.
Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive
| Chemical Name: | (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-3b,4,4a,6,6a,7a,7b,8b,9,10-Decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one |
| Purity: | ≥98% (HPLC) |
