Urotensin-II R: Small Molecules and Peptides
Urotensin-II Receptor belongs to the G protein-coupled receptor 1 family. Urotensin-II R is a high affinity receptor for Urotensin-2 and Urotensin-2B. The activity of Urotensin-II R is mediated by a G protein that activates a phosphatidylinositol-calcium second messenger system. It is most abundantly expressed in the heart and pancreas. Urotensin-II R has been correlated with human cortico-adrenal carcinoma proliferation.
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Urotensin-II R: Small Molecules and Peptides
Urotensin-II Receptor belongs to the G protein-coupled receptor 1 family. Urotensin-II R is a high affinity receptor for Urotensin-2 and Urotensin-2B. The activity of Urotensin-II R is mediated by a G protein that activates a phosphatidylinositol-calcium second messenger system. It is most abundantly expressed in the heart and pancreas. Urotensin-II R has been correlated with human cortico-adrenal carcinoma proliferation.
High affinity, selective urotensin II (UT) receptor antagonist
| Chemical Name: | N-[(1R)-1-[3'-(Aminocarbonyl)[1,1'-biphenyl]-4-yl]-2-(1-pyrrolidinyl)ethyl]-6,7-dichloro-2,3-dihydro-N-methyl-3-oxo-4H-1,4-benzoxazine-4-acetamide hydrochloride |
| Purity: | ≥98% (HPLC) |
