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TRANCE/TNFSF11/RANK L: Simple Plex

TRANCE (TNF-related activation-induced cytokines), also known as RANK Ligand, OPGL, or ODF, is a TNF superfamily ligand produced by osteoblasts, bone marrow stromal cells, and activated T cells. It signals through RANK and is antagonized by the decoy receptor Osteoprotegerin. TRANCE stimulates bone resorption, is required for osteoclast differentiation, and is associated with the development of osteoporosis, vascular calcification, osteopetrosis, and progestin-induced breast cancer. It also mediates body temperature regulation and is essential for the development of a lactating mammary gland.

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2 results for "TRANCE/TNFSF11/RANK L Simple Plex" in Products

2 results for "TRANCE/TNFSF11/RANK L Simple Plex" in Products

TRANCE/TNFSF11/RANK L: Simple Plex

TRANCE (TNF-related activation-induced cytokines), also known as RANK Ligand, OPGL, or ODF, is a TNF superfamily ligand produced by osteoblasts, bone marrow stromal cells, and activated T cells. It signals through RANK and is antagonized by the decoy receptor Osteoprotegerin. TRANCE stimulates bone resorption, is required for osteoclast differentiation, and is associated with the development of osteoporosis, vascular calcification, osteopetrosis, and progestin-induced breast cancer. It also mediates body temperature regulation and is essential for the development of a lactating mammary gland.

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Applications: Simple Plex

Simple Plex Human TRANCE assay kit for use on Ella instrument. Contains cartridge, Sample Diluent SD13, and Wash Buffer.

Control for use with Human TRANCE/RANK L/TNFSF11 Simple Plex Assay Cartridge Kit

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