Sirtuin 2/SIRT2: Small Molecules and Peptides
Sirtuin 2, is a member of the class III histone deacetylases (HDACs) and has been implicated in many cellular processes that include histone deacetylation, gene silencing, chromosomal stability, and aging (3 - 4). The enzymatic activity of class III HDACs is nicotinamide adenine dinucleotide (NAD) dependent and insensitive to HDAC inhibitor trichostatin A.
2 results for "Sirtuin 2/SIRT2 Small Molecules and Peptides" in Products
2 results for "Sirtuin 2/SIRT2 Small Molecules and Peptides" in Products
Sirtuin 2/SIRT2: Small Molecules and Peptides
Sirtuin 2, is a member of the class III histone deacetylases (HDACs) and has been implicated in many cellular processes that include histone deacetylation, gene silencing, chromosomal stability, and aging (3 - 4). The enzymatic activity of class III HDACs is nicotinamide adenine dinucleotide (NAD) dependent and insensitive to HDAC inhibitor trichostatin A.
Selective inhibitor of SIRT2
| Chemical Name: | 2-[(4,6-Dimethyl-2-pyrimidinyl)thio]-N-[5-(1-naphthalenylmethyl)-2-thiazolyl]acetamide |
| Purity: | ≥98% (HPLC) |
Selective SIRT2 inhibitor; brain penetrant
| Chemical Name: | N-(3-Bromophenyl)-3-[(hexahydro-1H-azepin-1-yl)sulfonyl]benzamide |
| Purity: | ≥98% (HPLC) |