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196 results for "SHP-1" in Products

SHP-1 Products

The SH2 domain-containing phosphatases, SHP-1 and SHP-2, are well-studied cytosolic tyrosine phosphatases that share many structural and regulatory features. They both have two tandem SH2 domains at the N-terminus, followed by a catalytic domain, and an inhibitory C-terminus. Despite their structural similarity, the enzymes appear to have different physiological roles and exhibit different expression patterns. SHP-1 is highly expressed in hematopoietic tissues, and in general has a negative impact on lymphocyte signaling. In contrast, SHP-2 is widely expressed, and in general promotes signaling pathways that lead to differentiation, cell growth, or migration.

Protein tyrosine phosphatase inhibitor

Chemical Name: Trisodium vanadate
Protein tyrosine phosphatase inhibitor

Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #SR41-02
Applications: IHC, WB, ICC/IF, Flow, IP
Western Blot: SHP-1 Antibody (SR41-02) [NBP2-67321]
(10)
Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, IP
Western Blot: SHP-1 Antibody [NBP1-32179]
(9)

Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #7I1K3
Applications: IHC, WB, ICC/IF
Western Blot: SHP-1 Antibody (7I1K3) [NBP3-15669]
(8)
Reactivity: Human, Rat
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF
Immunocytochemistry/ Immunofluorescence: SHP-1 Antibody [NBP1-83276]
(8)

Contains 4 membranes - each spotted in duplicate with 59 different immunoreceptor antibodies

The Human Phospho-Immunoreceptor Array detects multiple tyrosine phosphorylated immunoreceptors in lysates prepared from cells activated by antibody mediated cross-linking of cell-surface immunoreceptors.
(2)
Source: E. coli
Accession #: P29350
Applications: EnzAct
R&D Systems Recombinant Proteins and Enzymes
Reactivity: Human, Mouse, Rat
Details: Goat IgG Polyclonal
Applications: IHC, WB, ELISA
Western Blot: SHP-1 Antibody [NB100-58968]
(3)
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