Sodium orthovanadate

Name: Sodium orthovanadate
Brand: Tocris Bioscience
SKU: 2821

Tocris Bioscience, part of Bio-Techne | Catalog # 2821

Citations (10)

COA / SDS

Protein tyrosine phosphatase inhibitor

Key Product Details

Description:	Protein tyrosine phosphatase inhibitor
Chemical Name:	Trisodium vanadate
Molecular Weight:	183.91

View Full Technical Details for Sodium orthovanadate

Technical Data
Citations

Biological Activity for Sodium orthovanadate

Sodium orthovanadate is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and ATPases. Suppresses p53-mediated apoptosis by transcription-dependent and -independent pathways.

Technical Data for Sodium orthovanadate

M. Wt	183.91
Formula	Na₃O₄V
Storage	Store at RT
CAS Number	13721-39-6
PubChem ID	61671
InChi Key	IHIXIJGXTJIKRB-UHFFFAOYSA-N
Smiles	O=[V]([O-])([O-])[O-].[Na+].[Na+].[Na+]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Sodium orthovanadate

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	18.39	100

Preparing Stock Solutions for Sodium orthovanadate

The following data is based on the product molecular weight 183.91.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	5.44 mL	27.19 mL	54.37 mL
5 mM	1.09 mL	5.44 mL	10.87 mL
10 mM	0.54 mL	2.72 mL	5.44 mL
50 mM	0.11 mL	0.54 mL	1.09 mL

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References for Sodium orthovanadate

References are publications that support the biological activity of the product.

Morita Sodium orthovanadate inhibits p53-mediated apoptosis. Cancer Res. 2010 PMID: 20048077
Hasegawa Therapeutic time window and dose dependence of neuroprotective effects of sodium orthovanadate following transient middle cerebral artery occlusion in rats. J.Pharmacol.Exp.Ther. 2006 PMID: 16461588
Matsumoto Sodium orthovanadate enhances proliferation of progenitor cells in the adult rat subventricular zone after focal cerebral ischemia. J.Pharmacol.Exp.Ther. 2006 PMID: 16782823
Ai Inhibition of small-intestinal sugar absorption mediated by sodium orthovanadate Na₃VO₄ in rats and its mechanisms. World J.Gastroenterol. 2004 PMID: 15534916