Proprotein Convertase 9/PCSK9: Proteome Profiler Antibody Arrays
PCSK9 (Proprotein Convertase 9, is a serine endoprotease that is highly expressed in the liver, intestine, and kidney. PCSK9 promotes the degradation of low density lipoprotein receptor (LDLR) by inducing receptor degradation in the lysosome following its internalization. PCSK9 regulates the amounts of LDLR in the circulation and hence, modulates cholesterol levels. Nonsense or loss-of-function mutations in PCSK9 are associated with decreased plasma LDL cholesterol levels.
4 results for "Proprotein Convertase 9/PCSK9 Proteome Profiler Antibody Arrays" in Products
4 results for "Proprotein Convertase 9/PCSK9 Proteome Profiler Antibody Arrays" in Products
Proprotein Convertase 9/PCSK9: Proteome Profiler Antibody Arrays
PCSK9 (Proprotein Convertase 9, is a serine endoprotease that is highly expressed in the liver, intestine, and kidney. PCSK9 promotes the degradation of low density lipoprotein receptor (LDLR) by inducing receptor degradation in the lysosome following its internalization. PCSK9 regulates the amounts of LDLR in the circulation and hence, modulates cholesterol levels. Nonsense or loss-of-function mutations in PCSK9 are associated with decreased plasma LDL cholesterol levels.
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
Contains 4 membranes - each spotted in duplicate with 35 different protease antibodies
Contains 4 membranes-each spotted in duplicate with 58 different obesity-related antibodies
Contains 4 membranes-2 spotted in duplicate with antibodies against 35 different proteases and 2 spotted in duplicate with antibodies against 32 different protease inhibitors