249 results for "Presenilin-1" in Products
Presenilin-1 Products
Presenilin-1 (PS-1) and Presenilin-2 (PS-2) are integral membrane proteins that contain multiple transmembrane domains. Both are predominantly located within the endoplasmic reticulum (ER) and early Golgi apparatus. They are primarily expressed in neurons and are ubiquitously expressed in the brain. PS-1 and PS-2 are proteolytically cleaved to generate an N-terminal fragment (NTF) and a C-terminal fragment (CTF). Mutations in the gene for Presenilin may play an important role in the pathology of Alzheimer's disease.
| Chemical Name: | (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine 1,1-dimethylethyl ester |
| Purity: | ≥99% (HPLC) |
| Chemical Name: | (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenylglycine 1,1-dimethylethyl ester |
| Purity: | ≥99% |
| Alternate Names: | Dibenzazepine,YO-01027 |
| Chemical Name: | N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide |
| Purity: | ≥98% (HPLC) |
| Alternate Names: | BMS-708163 |
| Chemical Name: | (2R)-2-[[(4-Chlorophenyl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoropentanamide |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 2-[(1R)-1-[[(4-Chlorophenyl)sulfonyl](2,5-difluorophenyl)amino]ethyl-5-fluorobenzenebutanoic acid |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | (2S)-2-[[(2S)-6,8-Difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]amino]-N-[1-[2-[(2,2-dimethylpropyl)amino]-1,1-dimethylethyl]-1H-imidazol-4-yl]pentanamide dihydrobromide |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | (2S)-2-Hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]butanamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #121121 |
| Applications: | WB, IHC |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #121130 |
| Applications: | WB |
Conjugate
Catalog #
Human Presenilin-1 N-Terminal Fragment Alexa Fluor™ Plus 680-conjugated Antibody
Catalog #:
FAB1491AFP680
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #121130 |
Human Presenilin-1 C-Terminal Fragment Alexa Fluor™ Plus 555-conjugated Antibody
Catalog #:
AF166AFP555
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #APS 18 |
| Applications: | IHC, WB, ELISA, ICC/IF, IP |
![Western Blot: Presenilin-1 Antibody (APS 18) [NB100-74510]](https://resources.bio-techne.com/images/products/Presenilin-1-Antibody-APS-18-Western-Blot-NB100-74510-img0013.jpg "Western Blot: Presenilin-1 Antibody (APS 18) [NB100-74510]")
| Applications: | WB, ELISA, MA, AP, PAGE |
![SDS-PAGE: Recombinant Human Presenilin-1 GST (N-Term) Protein [H00005663-Q01]](https://resources.bio-techne.com/images/products/qc_test-H00005663-Q01-1.jpg "SDS-PAGE: Recombinant Human Presenilin-1 GST (N-Term) Protein [H00005663-Q01]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #121121 |
| Applications: | WB, IHC |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
Conjugate
Catalog #
| Chemical Name: | N-[cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #121121 |
| Applications: | WB, IHC |
Conjugate
Catalog #
Human Presenilin-1 N-Terminal Fragment Alexa Fluor™ Plus 680-conjugated Antibody
Catalog #:
AF149AFP680
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
Human Presenilin-1 N-Terminal Fragment Alexa Fluor™ Plus 405-conjugated Antibody
Catalog #:
FAB1491AFP405
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #121130 |
Human Presenilin-1 N-Terminal Fragment Alexa Fluor™ Plus 594-conjugated Antibody
Catalog #:
FAB149AFP594
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #121121 |
Human Presenilin-1 C-Terminal Fragment Alexa Fluor™ Plus 405-conjugated Antibody
Catalog #:
AF166AFP405
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
Human Presenilin-1 N-Terminal Fragment Alexa Fluor™ Plus 405-conjugated Antibody
Catalog #:
FAB149AFP405
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #121121 |