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6 results for "PPAR alpha/NR1C1 Small Molecules and Peptides" in Products

PPAR alpha/NR1C1: Small Molecules and Peptides

Peroxisome proliferators are non-genotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family, termed peroxisome proliferator activated receptors (PPARs). Nuclear hormone receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Studies indicate that PPARs are activated by ...

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Highly selective, potent PPARα agonist. Orally active

Chemical Name: 2-[[4-[2-[[(Cyclohexylamino)carbonyl](4-cyclohexylbutyl)amino]ethyl]phenyl]thio]-2-methylpropanoic acid
Purity: ≥98% (HPLC)
Highly selective, potent PPARα agonist. Orally active

Selective PPARα agonist

Chemical Name: [[4-Chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl]thio]acetic acid
Purity: ≥98% (HPLC)
Selective PPARα agonist

Potent and selective PPARγ agonist; antidiabetic agent

Alternate Names: BRL 49653
Chemical Name: 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione
Purity: ≥98% (HPLC)
Potent and selective PPARγ agonist; antidiabetic agent

PPARα/γ agonist

Alternate Names: AZ 242
Chemical Name: (S)-2-Ethoxy-3-[4-[2-(4-methanesulfonyloxyphenyl)ethoxy]phenyl]propanoic acid
Purity: ≥98% (HPLC)
PPARα/γ agonist

PPARα antagonist

Chemical Name: N-((2S)-2-(((1Z)-1-Methyl-3-oxo-3-(4-(trifluoromethyl)phenyl)prop-1-enyl)amino)-3-(4-(2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy)phenyl)propyl)propanamide
Purity: ≥98% (HPLC)
PPARα antagonist

RXR agonist

Alternate Names: DHA
Chemical Name: (4Z,7Z,10Z,13Z,16Z,19Z)-4,7,10,13,16,19-Docosahexaenoic acid
Purity: ≥98%
RXR agonist
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