Tesaglitazar

Tocris Bioscience, part of Bio-Techne | Catalog # 3965

PPARα/γ agonist
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Key Product Details

Description

PPARα/γ agonist

Alternative Names

AZ 242

View all Non-selective PPAR Receptor Agonists »

Product Description

Tesaglitazar is a dual-specificity PPARα/γ agonist (IC50 values are 0.35 and 3.8 μM for PPARγ and PPARα respectively). Prevents atherosclerosis progression in E3L.CETP transgenic mice. Also reduces insulin resistance in obese Zucker rats. Orally active.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Product Specifications

Molecular Weight

408.47

Formula

C20H24O7S

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

(S)-2-Ethoxy-3-[4-[2-(4-methanesulfonyloxyphenyl)ethoxy]phenyl]propanoic acid

CAS Number

251565-85-2

PubChem ID

208901

InChI Key

CXGTZJYQWSUFET-IBGZPJMESA-N

SMILES

CS(OC1=CC=C(CCOC2=CC=C(C[C@H](OCC)C(O)=O)C=C2)C=C1)(=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 40.85 100
Ethanol 40.85 100

Preparing Stock Solutions for Tesaglitazar

The following data is based on the product molecular weight 408.47

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.45 mL 12.24 mL 24.48 mL
5 mM 0.49 mL 2.45 mL 4.90 mL
10 mM 0.24 mL 1.22 mL 2.45 mL
50 mM 0.05 mL 0.24 mL 0.49 mL

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Product Documents for Tesaglitazar

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Tesaglitazar

For research use only

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