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19 results for "PDE5A" in Products

PDE5A Products

PDE5A encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

Potent and highly selective PDE5 inhibitor; orally bioavailable

PDE inhibitor (non-selective)

Potent PDE5 inhibitor; orally active

Adenosine transport inhibitor

GPR35 agonist

USP10 and USP13 inhibitor; inhibits autophagy

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