58 results for "PD-1" in Products
PD-1 Products
PD-1 (Programmed Death-1 receptor) is a key regulator of the threshold of immune response and peripheral immune tolerance. It is expressed on activated T cells, B cells, monocytes, and dendritic cells and binds to PD-L1 or PD-L2. PD-1 ligation induces co-inhibitory signals in T cells promoting their apoptosis, anergy, and functional exhaustion. Many tumors overexpress PD-L1 to induce this inhibitory signaling pathway in immune cells. When PD-1 expressing immune cells come into contact with a ...
Clone J116 was used by HLDA to establish CD designation.
Recombinant Monoclonal Antibody
Recombinant Monoclonal Antibody
Recombinant Monoclonal Antibody
Recombinant Monoclonal Antibody
Recombinant Monoclonal Antibody
Recombinant Monoclonal Antibody
Recombinant Monoclonal Antibody