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11 results for "other-transcription-factor-inhibitors&view=expanded" in Products

Potent and selective Foxo1 inhibitor; orally bioavailable

Chemical Name:
5-Amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Purity:
≥98%
Potent and selective Foxo1 inhibitor; orally bioavailable

Selective inhibitor of ATF6α; sensitizes cells to ER stress

Chemical Name:
N-[1-[[2,4-bis(Trifluoromethyl)phenyl]methyl]-1H-pyrazol-4-yl]-5-(2-furanyl)-3-isoxazolecarboxamide
Purity:
≥98%
Selective inhibitor of ATF6α; sensitizes cells to ER stress

Selective Smad3 inhibitor; inhibits TGF-βR1 signaling

Chemical Name:
1,2,3,4-Tetrahydro-6,7-dimethoxy-2-[(2E)-3-(1-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-1-oxo-2-propenyl]-isoquinoline hydrochloride
Purity:
≥97%
Selective Smad3 inhibitor; inhibits TGF-βR1 signaling

Steroid receptor coactivator 3 (SRC-3) inhibitor

Chemical Name:
1-(2-Pyridinyl)ethanone 2-(1-methyl-1H-benzimidazol-2-yl)hydrazone hydrochloride
Purity:
≥98%
Steroid receptor coactivator 3 (SRC-3) inhibitor

Core binding factor inhibitor; attenuates hematopoiesis

Alternate Names:
CBF&#946-Runx1 inhibitor II
Chemical Name:
7-Chloro-1,3-dihydro-5-(1H-pyrrol-2-yl)-2H-1,4-benzodiazepin-2-one
Purity:
≥98%
Core binding factor inhibitor; attenuates hematopoiesis

Potent and reversible inhibitor of TEAD mediated Hippo/Yap signalling

Chemical Name:
4-[3-(2-Cyclohexylethoxy)benzoyl]-N-phenyl-1-piperazinecarboxamide
Purity:
≥98%
Potent and reversible inhibitor of TEAD mediated Hippo/Yap signalling

GLI antagonist; inhibits Hedgehog (Hh) signaling

Chemical Name:
2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethylbenzenamine
Purity:
≥98%
GLI antagonist; inhibits Hedgehog (Hh) signaling

Potent pan-TEAD inhibitor

Chemical Name:
N-[(1S)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide
Purity:
≥98%
Potent pan-TEAD inhibitor

Potent and selective CREB inhibitor

Chemical Name:
3-(3-Aminopropoxy)-N-[2-[[3-[[(4-chloro-2-hydroxyphenyl)amino]carbonyl]-2-naphthalenyl]oxy]ethyl]-2-naphthalenecarboxamide hydrochloride
Purity:
≥98%
Potent and selective CREB inhibitor

Benzodiazepine antagonist

Alternate Names:
Ro 15-1788
Chemical Name:
8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, ethyl ester
Purity:
≥99%
Benzodiazepine antagonist
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