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5 results for "NPY2R Small Molecules and Peptides" in Products

NPY2R: Small Molecules and Peptides

NPY2R is widely expressed in the central nervous system, with particularly high abundance in the hypothalamus. The hypothalamus is known to be important for appetite regulation and thus variants in this gene could be associated with obesity.

Potent, selective and competitive non-peptide NPY Y2 receptor antagonist; active in vivo

Alternate Names: BIIE 0246 2HCl,BIIE0246 2HCl
Chemical Name: N-[(1S)-4-[(Aminoiminomethyl)amino]-1-[[[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]amino]carbonyl]butyl]-1-[2-[4-(6,11-dihydro-6-oxo-5H-dibenz[b,e]azepin-11-yl)-1-piperazinyl]-2-oxoethyl]-cyclopentaneacetamide dihydrochloride
Purity: ≥98% (HPLC)
Potent, selective and competitive non-peptide NPY Y2 receptor antagonist; active in vivo

Selective NPY Y2 receptor agonist

Alternate Names: PYY 3-36
Purity: ≥95% (HPLC)
Selective NPY Y2 receptor agonist

Potent and selective D1-like agonist; orally active

Chemical Name: (1R-cis)-1-(Aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-[1H]-2-benzopyran-5,6-diol hydrochloride
Purity: ≥98% (HPLC)
Potent and selective D1-like agonist; orally active

NPY Y2 receptor antagonist

Chemical Name: N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide
Purity: ≥98% (HPLC)
NPY Y2 receptor antagonist

Potent NPY Y2 receptor antagonist

Chemical Name: N-[4-[(Dimethylamino)sulfonyl]phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide
Purity: ≥98% (HPLC)
Potent NPY Y2 receptor antagonist
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