A 77636 hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 1701

Potent and selective D1-like agonist; orally active
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Key Product Details

Description

Potent and selective D1-like agonist; orally active

View all Dopamine D1 and D5 Receptor Agonists »

Product Description

A 77636 hydrochloride is a potent and selective dopamine D1-like receptor agonist (pEC50 values are 8.97 and < 5 for D1-like and D2-like receptors respectively). Displays anti-Parkinsonian activity following oral administration in vivo. Exhibits 11-fold cell type bias over dopamine in a functional assay in U2 cells.

Product Specifications

Molecular Weight

365.90

Formula

C20H27NO3.HCl

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

(1R-cis)-1-(Aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-[1H]-2-benzopyran-5,6-diol hydrochloride

CAS Number

145307-34-2

PubChem ID

9811493

InChI Key

RSJAXPUYVJKAAA-JPGJPTAESA-N

SMILES

NC[C@@H]2O[C@H]([C@]35CC(CC(C5)C4)CC4C3)CC1=C(O)C(O)=CC=C12.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 36.59 100

Preparing Stock Solutions for A 77636 hydrochloride

The following data is based on the product molecular weight 365.90

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.73 mL 13.66 mL 27.33 mL
5 mM 0.55 mL 2.73 mL 5.47 mL
10 mM 0.27 mL 1.37 mL 2.73 mL
50 mM 0.05 mL 0.27 mL 0.55 mL

Calculators

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Product Documents for A 77636 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for A 77636 hydrochloride

For research use only

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