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NKp44/NCR2 Products

NKp30/NCR3, NKp44/NCR2, and NKp46/NCR1 are termed natural cytotoxicity receptors (NCR). These receptors are type I transmembrane proteins with 1-2 extracellular immunoglobulin domains, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmic tail. All are expressed almost exclusively by NK cells and play a major role in triggering NK-mediated killing of most tumor cell lines. NKp44 is induced upon activation of resting NK cells with IL-2 and can bind to viral hemagglutinins. NK-mediated dendritic cell (DC) recognition is highly dependent on engagement of NKp30 and may result in lysis of the DC.

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176 results for "NKp44/NCR2" in Products

176 results for "NKp44/NCR2" in Products

NKp44/NCR2 Products

NKp30/NCR3, NKp44/NCR2, and NKp46/NCR1 are termed natural cytotoxicity receptors (NCR). These receptors are type I transmembrane proteins with 1-2 extracellular immunoglobulin domains, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmic tail. All are expressed almost exclusively by NK cells and play a major role in triggering NK-mediated killing of most tumor cell lines. NKp44 is induced upon activation of resting NK cells with IL-2 and can bind to viral hemagglutinins. NK-mediated dendritic cell (DC) recognition is highly dependent on engagement of NKp30 and may result in lysis of the DC.

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Reactivity: Human
Details: Mouse IgG2a Monoclonal Clone #253415
Applications: Flow
Detection of NKp44/NCR2 antibody in Human PBMCs antibody by Flow Cytometry.
Reactivity: Human
Details: Mouse IgG2a Monoclonal Clone #253415
Applications: Flow, AgAct, CyTOF-reported
Human NKp44/NCR2 Antibody Induces IFN-? Secretion antibody in Activated Human NK Cells.

Analyzed by SEC-MALS

Source: HEK293
Accession #: O95944.2
Applications: BA
(3)
Reactivity: Human
Details: Mouse IgG2a Monoclonal Clone #253415
Applications: Flow
Detection of NKp44/NCR2 antibody in Human PBMCs antibody by Flow Cytometry.

Biotinylated

Source: CHO
Accession #: CAB39168.1
Applications: BA
(2)
Reactivity: Human
Details: Mouse IgG2a Monoclonal Clone #253415
Applications: Flow
Reactivity: Human
Details: Mouse IgG2a Monoclonal Clone #253415
Applications: Flow
Reactivity: Human
Details: Mouse IgG2a Monoclonal Clone #253415
Applications: Flow
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