Cyno Monkey NKp44/NCR2 (NP_001306466.1) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC3201
Key Product Details
Species
Cynomolgus Monkey
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: NKp44/NCR2
NKp30/NCR3, NKp44/NCR2, and NKp46/NCR1 are termed natural cytotoxicity receptors (NCR). These receptors are type I transmembrane proteins with 1-2 extracellular immunoglobulin domains, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmic tail. All are expressed almost exclusively by NK cells and play a major role in triggering NK-mediated killing of most tumor cell lines. NKp44 is induced upon activation of resting NK cells with IL-2 and can bind to viral hemagglutinins. NK-mediated dendritic cell (DC) recognition is highly dependent on engagement of NKp30 and may result in lysis of the DC.
Long Name
NK Cell Activating Receptor
Alternate Names
CD336, LY95, NCR2
Gene Symbol
NCR2
UniProt
Additional NKp44/NCR2 Products
Product Documents for Cyno Monkey NKp44/NCR2 (NP_001306466.1) VersaClone cDNA
Product Specific Notices for Cyno Monkey NKp44/NCR2 (NP_001306466.1) VersaClone cDNA
For research use only
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