NKp44/NCR2 Products
NKp30/NCR3, NKp44/NCR2, and NKp46/NCR1 are termed natural cytotoxicity receptors (NCR). These receptors are type I transmembrane proteins with 1-2 extracellular immunoglobulin domains, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmic tail. All are expressed almost exclusively by NK cells and play a major role in triggering NK-mediated killing of most tumor cell lines. NKp44 is induced upon activation of resting NK cells with IL-2 and can bind to viral hemagglutinins. NK-mediated dendritic cell (DC) recognition is highly dependent on engagement of NKp30 and may result in lysis of the DC.
20 results for "NKp44/NCR2" in Products
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NKp44/NCR2 Products
NKp30/NCR3, NKp44/NCR2, and NKp46/NCR1 are termed natural cytotoxicity receptors (NCR). These receptors are type I transmembrane proteins with 1-2 extracellular immunoglobulin domains, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmic tail. All are expressed almost exclusively by NK cells and play a major role in triggering NK-mediated killing of most tumor cell lines. NKp44 is induced upon activation of resting NK cells with IL-2 and can bind to viral hemagglutinins. NK-mediated dendritic cell (DC) recognition is highly dependent on engagement of NKp30 and may result in lysis of the DC.
20 results for "NKp44/NCR2" in Products
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #253415 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #253415 |
Applications : | CyTOF-ready, Flow Cytometry, Functional Assay |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #253415 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #253415 |
Applications : | Flow Cytometry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Functional Assay, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #253422 |
Applications : | Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #253424 |
Applications : | Immunocytochemistry/Immunofluorescence |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #253415 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #253415 |
Applications : | Flow Cytometry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Source : | HEK293 |
Accession # : | O95944.2 |
Applications : | Bioactivity |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #253415 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #253415 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #253415 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #253415 |
Applications : | Flow Cytometry |
Source : | NS0 |
Accession # : | CAB31968.1 |
Applications : | Bioactivity |
Contains 4 membranes - each spotted in duplicate with 59 different immunoreceptor antibodies