4 results for "NHE1/SLC9A1 Small Molecules and Peptides" in Products
NHE1/SLC9A1: Small Molecules and Peptides
The Na+/H+ antiporter (SLC9A1) is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells. It is specifically inhibited by the diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, tumor promoters, and others (Mattei et al., 1988 [PubMed 2846238]).[supplied by OMIM]
Potent and selective NHE1 inhibitor
| Chemical Name: | 4-(1-Acetyl-4-piperidinyl)-N-(aminoiminomethyl)-3-(trifluoromethyl)benzamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective NHE1 inhibitor
| Alternate Names: | CP 597396 |
| Chemical Name: | [1-(Quinolin-5-yl)-5-cyclopropyl-1H-pyrazole-4-carbonyl]guanidine dihydrochloride |
| Purity: | ≥98% (HPLC) |
Selective NHE1 inhibitor; cardioprotective and antitumor
| Alternate Names: | HOE 642 |
| Chemical Name: | N-(Aminoiminomethyl)-4-(1-methylethyl)-3-(methylsulfonyl)benzamide |
| Purity: | ≥98% (HPLC) |
Inhibits TRPP3-mediated currents; also inhibits the Na+/H+ exchanger (NHE)
| Alternate Names: | Ethylisopropyl amiloride |
| Chemical Name: | 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide |
| Purity: | ≥98% (HPLC) |
