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3 results for "NFkB/IkB Activators" in Products

NFkB/IkB Activators Products

NF-κB (nuclear factor-kappa B) is a rapidly acting primary transcription factor found in all cell types. It is involved in cellular responses to stimuli such as cytokines and stress and plays a key role in regulating the immune response to infection. In unstimulated cells NF-κB dimers are sequestered inactively in the cytoplasm by a protein complex called inhibitor of kappa B (IκB). IκB inactivates NF-κB by masking the nuclear localization signals (NLS).

Activation of ...

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KDM4A inhibitor; also NF-κB activator

Antitumor and anti-HIV agent; activates NF-κB. Also TGR5 agonist

Potent and selective inhibitor of USP21; also NF-κB activator

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