7 results for "Nav1.6 Small Molecules and Peptides" in Products
Nav1.6: Small Molecules and Peptides
Voltage-dependent sodium channels, such as SCN8A, are responsible for the initial membrane depolarization that occurs during generation of action potentials in most electrically excitable cells (Plummer et al., 1998 [PubMed 9828131]).[supplied by OMIM]
Potent hNav1.4, rNav1.6 and rNav1.7 channel activator
| Purity: | ≥95% (HPLC) |
Cardiac Na+ channel blocker. Antiarrhythmic
| Chemical Name: | N-(2-Piperidylmethyl)-2,5-bis-(2,2,2-trifluoroethoxy)benzamide acetate |
| Purity: | ≥98% (HPLC) |
Antianginal, activates pyruvate dehydrogenase
| Alternate Names: | RS 43285 |
| Chemical Name: | N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
NaV blocker; neuroprotective
| Alternate Names: | 619C89 |
| Chemical Name: | 2-(4-Methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)-4-pyrimidinamine |
| Purity: | ≥98% (HPLC) |
Inhibitor of neuronal NaV channels; anticonvulsant
| Alternate Names: | CBZ |
| Chemical Name: | 5H-Dibenz[b,f]azepine-5-carboxamide |
| Purity: | ≥98% (HPLC) |
Na+ channel blocker; antiarrhythmic agent
| Alternate Names: | Ko 1173 |
| Chemical Name: | 1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Blocks voltage-sensitive Na+ and Ca2+ channels (T-type)
| Alternate Names: | AD 810,CI 912 |
| Chemical Name: | 1,2-Benzisoxazole-3-methanesulfonamide |
| Purity: | ≥99% (HPLC) |
