4 results for "Na+/H+ Exchanger Inhibitors" in Products
Na+/H+ Exchanger Inhibitors Products
Sodium-hydrogen exchangers (Na+/H+ exchangers, NHE) are ATP-independent membrane glycoprotein transporters that are involved in the regulation of intracellular pH, cell volume and the cellular response to hormones and mitogens. The transporters mediate the simultaneous efflux of a hydrogen ion and the influx of a sodium ion across the plasma membrane, the driving force being the inwardly directed electrochemical Na+ gradient. There are nine known mammalian NHE isoforms (NHE1-9), all of which ...
Inhibits TRPP3-mediated currents; also inhibits the Na+/H+ exchanger (NHE)
| Alternate Names: | Ethylisopropyl amiloride |
| Chemical Name: | 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide |
| Purity: | ≥98% (HPLC) |
Na+ channel blocker; also I2 imidazoline ligand
| Chemical Name: | 3,5-Diamino-N-(aminoiminomethyl)-6-chloropyrazinecarboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective NHE1 inhibitor; cardioprotective and antitumor
| Alternate Names: | HOE 642 |
| Chemical Name: | N-(Aminoiminomethyl)-4-(1-methylethyl)-3-(methylsulfonyl)benzamide |
| Purity: | ≥98% (HPLC) |
Selective NHE1 inhibitor
| Alternate Names: | CP 597396 |
| Chemical Name: | [1-(Quinolin-5-yl)-5-cyclopropyl-1H-pyrazole-4-carbonyl]guanidine dihydrochloride |
| Purity: | ≥98% (HPLC) |
